Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition (Q27696197)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Christopher J. Schofield

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Jürgen Brem

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Wei Shen Aik

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Anna M Rydzik

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Matthew B Avison

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Michael A McDonough

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

10

Timothy D W Claridge

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Sander S van Berkel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Ilaria Pettinati

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Klaus-Daniel Umland

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

James Spencer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

publication date

17 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

1084-1090

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

Updated functional classification of beta-lactamases

23 February 2020

cites work

1 reference

Kinetics of avibactam inhibition against Class A, C, and D β-lactamases

20 April 2017

1 reference

Accurate design of co-assembling multi-component protein nanomaterials

20 April 2017

1 reference

Phasercrystallographic software

20 April 2017

1 reference

Structural Insights into the Subclass B3 Metallo- -Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor Mercaptoacetate

20 April 2017

1 reference

Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R -thiomandelic acid

20 April 2017

1 reference

The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril

20 April 2017

1 reference

New Delhi metallo-β-lactamase: structural insights into β-lactam recognition and inhibition

20 April 2017

1 reference

Privileged scaffolds for library design and drug discovery

20 April 2017

1 reference

Antibiotics in the clinical pipeline in 2013.

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Bridging cell wall biosynthesis and bacterial morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Metallo-beta-lactamases: the quiet before the storm?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Metallo-β-lactamases: a last frontier for β-lactams?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

The mechanisms of catalysis by metallo beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Metallo-beta-lactamases: novel weaponry for antibiotic resistance in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Proliferation and significance of clinically relevant β-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Development of new drugs for an old target: the penicillin binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

The inhibition of metallo-beta-lactamase by thioxo-cephalosporin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Metallo-β-lactamase: inhibitors and reporter substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Assay platform for clinically relevant metallo-β-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Thiols as classical and slow-binding inhibitors of IMP-1 and other binuclear metallo-beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Chromophore-linked substrate (CLS405): probing metallo-β-lactamase activity and inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

19F NMR: a valuable tool for studying biological events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Global spread of Carbapenemase-producing Enterobacteriaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor combination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Privileged Scaffolds or Promiscuous Binders: A Comparative Study on Rhodanines and Related Heterocycles in Medicinal Chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Rhodanine as a privileged scaffold in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

Rhodanine carboxylic acids as novel inhibitors of histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2110

The synthesis and SAR of rhodanines as novel class C beta-lactamase inhibitors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25411887

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dissociation constants and reactions of 3-phenyl and 3-cyclohexyl-2-mercaptopropenoic and 3-phenyl-2-mercaptopropanoic acids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25411887

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25411887

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEM.2110

2 references

Consolidated OpenCitations Corpus – April 2017

4303658

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 February 2020

1038260729

0 references

4303658

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4303658

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411887%20AND%20SRC:MED&resulttype=core&format=json