The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis (Q27703519)

1

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Chuangye Yan

2

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Rui Bai

3

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Lin Wang

4

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Min Huang

5

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Catherine C L Wong

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

6

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language of work or name

English

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publication date

29 January 2016

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published in

Science

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volume

351

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issue

6272

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page(s)

466-75

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cites work

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Structure of a yeast spliceosome at 3.6-angstrom resolution

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Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy

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The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP.

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Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP

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Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein

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Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants

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Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8

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Functional organization of the Sm core in the crystal structure of human U1 snRNP

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Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

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Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA

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Structure and assembly of the SF3a splicing factor complex of U2 snRNP

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U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs

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Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

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Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

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The spliceosome: disorder and dynamics defined

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Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns

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Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

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Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy

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The architecture of the spliceosomal U4/U6.U5 tri-snRNP.

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Crystal structure of Prp8 reveals active site cavity of the spliceosome

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Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.

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Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes

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Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

21 January 2018

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Beam-induced motion correction for sub-megadalton cryo-EM particles.

21 January 2018

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High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

21 January 2018

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Refinement of protein structures into low-resolution density maps using rosetta

21 January 2018

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High-resolution comparative modeling with RosettaCM.

21 January 2018

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EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.AAD6466

Metal ion catalysis during splicing of premessenger RNA

21 January 2018

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Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement

21 January 2018

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9 October 2024

https://opencitations.net/index/api/v1/citations/10.1038/NMETH.3286

Identifiers

DOI

10.1126/SCIENCE.AAD6466

1 reference

Consolidated OpenCitations Corpus – April 2017

release_xvz5pvbaojambaydahiaxdw7qe

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Fatcat

https://api.fatcat.wiki/v0/release/xvz5pvbaojambaydahiaxdw7qe

mapped directly with Wikidata item

24 November 2022

based on heuristic

4027510

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Consolidated OpenCitations Corpus – April 2017

4027510

PubMed publication ID

26743623

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Consolidated OpenCitations Corpus – April 2017