Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-Like Proteins Support a Highly Dynamic Domain Architecture (Q27728008)

5

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13 June 2020

author name string

Bradley R Miller

1

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13 June 2020

Eric J Drake

2

1 reference

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13 June 2020

Ce Shi

3

1 reference

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13 June 2020

Courtney C Aldrich

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597544%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

13 June 2020

language of work or name

English

0 references

publication date

5 September 2016

0 references

published in

1 reference

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13 June 2020

volume

291

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13 June 2020

issue

43

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13 June 2020

page(s)

22559-22571

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Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases

13 June 2020

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1 reference

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Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase

20 March 2017

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Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry

20 March 2017

1 reference

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Crystal structures of the first condensation domain of CDA synthetase suggest conformational changes during the synthetic cycle of nonribosomal peptide synthetases

20 March 2017

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Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

20 March 2017

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Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains

20 March 2017

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Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains

20 March 2017

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Structural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide Synthetases

20 March 2017

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Solution structure of Rv2377c-founding member of the MbtH-like protein family

20 March 2017

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20 March 2017

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Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase

20 March 2017

1 reference

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Crystal structure of the termination module of a nonribosomal peptide synthetase

20 March 2017

1 reference

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The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa

20 March 2017

1 reference

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Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE

20 March 2017

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iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

20 March 2017

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Inference of macromolecular assemblies from crystalline state

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency

20 March 2017

1 reference

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Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product

20 March 2017

1 reference

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Identification of new, conserved, non-ribosomal peptide synthetases from fluorescent pseudomonads involved in the biosynthesis of the siderophore pyoverdine

20 March 2017

1 reference

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Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin

20 March 2017

1 reference

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A deliberate approach to screening for initial crystallization conditions of biological macromolecules

20 March 2017

1 reference

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Structural Biology of Nonribosomal Peptide Synthetases

7 April 2017

1 reference

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Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

29 September 2017

1 reference

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The structural biology of biosynthetic megaenzymes

29 September 2017

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Insights into the chemical logic and enzymatic machinery of NRPS assembly lines

29 September 2017

1 reference

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Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis

29 September 2017

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Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases.

29 September 2017

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Role of MbtH-like proteins in the adenylation of tyrosine during aminocoumarin and vancomycin biosynthesis.

29 September 2017

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Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

29 September 2017

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Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins

29 September 2017

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MbtH-like proteins as integral components of bacterial nonribosomal peptide synthetases

29 September 2017

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Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase

29 September 2017

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How to tailor non-ribosomal peptide products--new clues about the structures and mechanisms of modifying enzymes

29 September 2017

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Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis

29 September 2017

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Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines

29 September 2017

1 reference

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Reconstitution and characterization of the Escherichia coli enterobactin synthetase from EntB, EntE, and EntF.

29 September 2017

1 reference

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Enzymatic tailoring of ornithine in the biosynthesis of the Rhizobium cyclic trihydroxamate siderophore vicibactin

29 September 2017

1 reference

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Enterobactin biosynthesis in Escherichia coli: isochorismate lyase (EntB) is a bifunctional enzyme that is phosphopantetheinylated by EntD and then acylated by EntE using ATP and 2,3-dihydroxybenzoate.

2 June 2018

1 reference

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Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics

2 June 2018

1 reference

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Dissection of the EntF condensation domain boundary and active site residues in nonribosomal peptide synthesis

21 January 2018

1 reference

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Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.

21 January 2018

1 reference

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Importance of the MbtH-like protein TioT for production and activation of the thiocoraline adenylation domain of TioK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.746297

Enzymatic Evidence for a Revised Congocidine Biosynthetic Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.746297

A method to produce microseed stock for use in the crystallization of biological macromolecules

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27597544

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M116.746297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597544%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597544%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference