Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma (Q27851797)

1

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T Nagai

3

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T Inoue

4

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K Ueshima

5

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N Nishida

6

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T Watanabe

7

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T Sakurai

British Journal of Cancer

8

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language of work or name

English

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publication date

5 June 2012

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published in

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volume

106

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issue

12

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page(s)

1997-2003

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cites work

Sorafenib in advanced hepatocellular carcinoma

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Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

20 March 2017

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Mammalian MAP kinase signalling cascades

20 March 2017

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MAP kinase signalling pathways in cancer

20 March 2017

1 reference

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Tumour stem cells and drug resistance

7 April 2017

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

7 April 2017

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Signaling pathways governing tumor angiogenesis

7 April 2017

1 reference

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CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling

29 September 2017

1 reference

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The role of signaling pathways in the development and treatment of hepatocellular carcinoma

29 September 2017

1 reference

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Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

29 September 2017

1 reference

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Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

29 September 2017

1 reference

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Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis

29 September 2017

1 reference

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Identification and characterization of tumorigenic liver cancer stem/progenitor cells

29 September 2017

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Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.

29 September 2017

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Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

29 September 2017

1 reference

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Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

29 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2012.145

Activation of c-Jun N-terminal kinase in non-cancerous liver tissue predicts a high risk of recurrence after hepatic resection for hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2012.145

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2012.145

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2012.145

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22596232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase II study of sorafenib in patients with advanced hepatocellular carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22596232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJC.2012.145

1 reference

Dimensions Publication ID

3125596

1050722885

0 references

3125596

1 reference

1 reference

1 reference