Mammalian MAP kinase signalling cascades (Q28204140)

New insights into the control of MAP kinase pathways

Europe PubMed Central

title

Mammalian MAP kinase signalling cascades (English)

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author name string

L Chang

series ordinal

1

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M Karin

series ordinal

2

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language of work or name

English

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publication date

1 March 2001

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published in

Nature

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volume

410

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page(s)

37-40

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issue

6824

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cites work

1 reference

7 January 2021

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

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7 January 2021

MAP kinase pathways in yeast: for mating and more

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7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

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7 January 2021

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

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7 January 2021

A mammalian scaffold complex that selectively mediates MAP kinase activation

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7 January 2021

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

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7 January 2021

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

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7 January 2021

An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg.

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7 January 2021

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

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7 January 2021

A conserved docking motif in MAP kinases common to substrates, activators and regulators

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7 January 2021

Regulation of transcription by MAP kinase cascades

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7 January 2021

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

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7 January 2021

Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

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7 January 2021

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

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7 January 2021

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

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7 January 2021

Regulation of carbamoyl phosphate synthetase by MAP kinase

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7 January 2021

A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1.

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7 January 2021

The protein kinase p90 rsk as an essential mediator of cytostatic factor activity.

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7 January 2021

Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90Rsk.

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7 January 2021

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

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7 January 2021

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

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7 January 2021

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

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7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

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7 January 2021

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

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7 January 2021

Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli

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7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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7 January 2021

The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest

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7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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7 January 2021

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

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7 January 2021

Selective requirement for MAP kinase activation in thymocyte differentiation.

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7 January 2021

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

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7 January 2021

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

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7 January 2021

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

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7 January 2021

SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis

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7 January 2021

c-Jun is essential for normal mouse development and hepatogenesis

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7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

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7 January 2021

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

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7 January 2021

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

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7 January 2021

Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.

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7 January 2021

Defective T Cell Differentiation in the Absence of Jnk1

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7 January 2021

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

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7 January 2021

JNK is required for effector T-cell function but not for T-cell activation

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7 January 2021

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.

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7 January 2021

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

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7 January 2021

Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development

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7 January 2021

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

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7 January 2021

Identifiers

DOI

10.1038/35065000

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

488638

1029421135

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488638

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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