MicroRNAs: small RNAs with a big role in gene regulation (Q27860896)

Europe PubMed Central

title

MicroRNAs: small RNAs with a big role in gene regulation (English)

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main subject

pre-miRNA processing

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0031054

primary miRNA processing

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Gene Ontology release 2020-05-02

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GOA release 2020-03-11

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2

Gregory J Hannon

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author name string

Lin He

series ordinal

1

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language of work or name

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July 2004

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published in

Nature Reviews Genetics

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volume

5

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page(s)

522-31

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issue

7

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cites work

Role of microRNAs in plant and animal development

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A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans

20 April 2017

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

20 April 2017

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The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

20 April 2017

1 reference

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

20 April 2017

1 reference

The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

20 April 2017

1 reference

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

20 April 2017

1 reference

The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor

20 April 2017

1 reference

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

20 April 2017

1 reference

Identification of tissue-specific microRNAs from mouse

20 April 2017

1 reference

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

20 April 2017

1 reference

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

20 April 2017

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The nuclear RNase III Drosha initiates microRNA processing

20 April 2017

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MicroRNA maturation: stepwise processing and subcellular localization

20 April 2017

1 reference

20 April 2017

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

20 April 2017

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RNA interference is mediated by 21- and 22-nucleotide RNAs

20 April 2017

1 reference

RNA-directed DNA methylation in Arabidopsis

20 April 2017

1 reference

Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

20 April 2017

1 reference

Prediction of plant microRNA targets

20 April 2017

1 reference

MicroRNA-directed cleavage of HOXB8 mRNA

20 April 2017

1 reference

Role for a bidentate ribonuclease in the initiation step of RNA interference

20 April 2017

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

20 April 2017

1 reference

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

20 April 2017

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Numerous microRNPs in neuronal cells containing novel microRNAs

20 April 2017

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New microRNAs from mouse and human

20 April 2017

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Nuclear export of microRNA precursors

20 April 2017

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

20 April 2017

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

20 April 2017

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Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

20 April 2017

1 reference

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

20 April 2017

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Structure and conserved RNA binding of the PAZ domain

20 April 2017

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Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

20 April 2017

1 reference

CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana

20 April 2017

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Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway

20 April 2017

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Asymmetry in the assembly of the RNAi enzyme complex

20 April 2017

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Functional siRNAs and miRNAs Exhibit Strand Bias

20 April 2017

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bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

20 April 2017

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The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

20 April 2017

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

20 April 2017

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Identification of novel genes coding for small expressed RNAs

20 April 2017

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An extensive class of small RNAs in Caenorhabditis elegans

20 April 2017

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Identification of many microRNAs that copurify with polyribosomes in mammalian neurons

20 April 2017

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20 April 2017

The microRNA Registry

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20 April 2017

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Vertebrate microRNA genes

20 April 2017

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The microRNAs of Caenorhabditis elegans

20 April 2017

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Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity

20 April 2017

1 reference

Embryonic stem cell-specific MicroRNAs

20 April 2017

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The small RNA profile during Drosophila melanogaster development

20 April 2017

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High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma

20 April 2017

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

20 April 2017

1 reference

Dicer is essential for mouse development

20 April 2017

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MicroRNAs modulate hematopoietic lineage differentiation

20 April 2017

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Prediction of mammalian microRNA targets

20 April 2017

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Identification of Drosophila MicroRNA targets

20 April 2017

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

20 April 2017

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A biochemical framework for RNA silencing in plants

20 April 2017

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MicroRNAs: genomics, biogenesis, mechanism, and function

20 April 2017

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

20 April 2017

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A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

20 April 2017

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Heterochromatin and epigenetic control of gene expression

20 April 2017

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A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development

20 April 2017

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Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA

20 April 2017

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siRNAs can function as miRNAs

20 April 2017

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Argonaute2, a link between genetic and biochemical analyses of RNAi

20 April 2017

1 reference

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

20 April 2017

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A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

20 April 2017

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The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

20 April 2017

1 reference

Control of leaf morphogenesis by microRNAs

20 April 2017

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Plasmid copy number control: an ever-growing story

20 April 2017

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X inactivation: Tsix and Xist as yin and yang

31 March 2020

1 reference

MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing

31 March 2020

1 reference

microRNAs: runts of the genome assert themselves

31 March 2020

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Control of developmental timing by micrornas and their targets

31 March 2020

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31 March 2020

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Mutations that lead to reiterations in the cell lineages of C. elegans

31 March 2020

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Heterochronic mutants of the nematode Caenorhabditis elegans.

31 March 2020

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Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development

31 March 2020

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The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch

31 March 2020

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A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.

31 March 2020

1 reference

The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target.

31 March 2020

1 reference

The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.

31 March 2020

1 reference

Transcriptional silencing and promoter methylation triggered by double-stranded RNA

31 March 2020

1 reference

Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.

31 March 2020

1 reference

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

31 March 2020

1 reference

31 March 2020

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Sequence requirements for micro RNA processing and function in human cells

31 March 2020

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RNase III enzymes and the initiation of gene silencing

31 March 2020

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Evidence for nuclear processing of plant micro RNA and short interfering RNA precursors

31 March 2020

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The long and short of siRNAs

31 March 2020

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DICER-LIKE1: blind men and elephants in Arabidopsis development

31 March 2020

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A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

31 March 2020

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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

31 March 2020

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R2D2 leads the silencing trigger to mRNA's death star.

31 March 2020

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MicroRNAs: a role in plant development

31 March 2020

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A micrococcal nuclease homologue in RNAi effector complexes

31 March 2020

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A microRNA array reveals extensive regulation of microRNAs during brain development

31 March 2020

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The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

31 March 2020

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Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis

31 March 2020

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A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal

31 March 2020

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Radial patterning of Arabidopsis shoots by class III HD-ZIP and KANADI genes

31 March 2020

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microRNA-mediated repression of rolled leaf1 specifies maize leaf polarity.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1379

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

79471

1001799892

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Fatcat ID

release_ru4fbazldnd4hmesvvuza3qxg4

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Fatcat

https://api.fatcat.wiki/v0/release/ru4fbazldnd4hmesvvuza3qxg4

mapped directly with Wikidata item

24 November 2022

based on heuristic

79471

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference