Beta-cell CaV channel regulation in physiology and pathophysiology (Q27863802)

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

PubMed

volume

288

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page(s)

E16-28

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issue

1

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cites work

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Electrophysiology of the pancreatic beta-cell

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Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

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Cyclic GMP depresses hippocampal Ca2+ current through a mechanism independent of cGMP-dependent protein kinase

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G protein modulation of voltage-gated calcium channels

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CaM kinase II: a protein kinase with extraordinary talents germane to insulin exocytosis

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Inositol hexakisphosphate stimulates non-Ca2+-mediated and primes Ca2+-mediated exocytosis of insulin by activation of protein kinase C

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Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

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The alpha2-adrenergic receptor is more effective than the galanin receptor in activating G-proteins in RINm5F beta-cell membranes

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Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits

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Modulation of ion-channel function by G-protein-coupled receptors

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Voltage dependent calcium channels in adrenal glomerulosa cells and in insulin producing cells

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Involvement of protein kinase C-epsilon in inositol hexakisphosphate-induced exocytosis in mouse pancreatic beta-cells

21 January 2018

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Inositol hexakisphosphate promotes dynamin I- mediated endocytosis

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Activation of alpha 2-adrenergic receptors decreases Ca2+ influx to inhibit insulin secretion in a hamster beta-cell line: an action mediated by a guanosine triphosphate-binding protein

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[Ca2+]i regulates trafficking of Cav1.3 (alpha1D Ca2+ channel) in insulin-secreting cells

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Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells

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Downregulation of the voltage-dependent calcium channel (VDCC) beta-subunit mRNAs in pancreatic islets of type 2 diabetic rats

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Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.

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Modulation of L-type Ca(2+) channels by distinct domains within SNAP-25.

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Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes

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Syntaxin-3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines

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Voltage-activated calcium and potassium currents in human pancreatic beta-cells

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A calcium-dependent chloride current in insulin-secreting beta TC-3 cells

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cAMP-dependent phosphorylation of the cardiac-type alpha 1 subunit of the voltage-dependent Ca2+ channel in a murine pancreatic beta-cell line

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Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

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Inactivation of voltage-dependent calcium current in an insulinoma cell line

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beta-Cell death during progression to diabetes

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Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

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Normalization of intracellular Ca(2+) induces a glucose-responsive state in glucose-unresponsive beta-cells

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Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas

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Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain

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Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells

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Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice

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Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells

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The role of serine/threonine protein phosphatases in exocytosis

21 January 2018

1 reference

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Ca2+ channel moving tail: link between Ca2+-induced inactivation and Ca2+ signal transduction

21 January 2018

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A Japanese family with spinocerebellar ataxia type 6 which includes three individuals homozygous for an expanded CAG repeat in the SCA6/CACNL1A4 gene.

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Primary structure of the receptor for calcium channel blockers from skeletal muscle

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Multiple types of neuronal calcium channels and their selective modulation

21 January 2018

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Functional coupling between 'R-type' Ca2+ channels and insulin secretion in the insulinoma cell line INS-1

21 January 2018

1 reference

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New isoform of the neuronal Ca2+ channel alpha1E subunit in islets of Langerhans and kidney--distribution of voltage-gated Ca2+ channel alpha1 subunits in cell lines and tissues

21 January 2018

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21 January 2018

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A low voltage-activated Ca2+ current mediates cytokine-induced pancreatic beta-cell death

21 January 2018

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21 January 2018

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21 January 2018

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The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

21 January 2018

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Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients

21 January 2018

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The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes

21 January 2018

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Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells

21 January 2018

1 reference

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Inositol hexakisphosphate increases L-type Ca2+ channel activity by stimulation of adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00042.2004

Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis.

21 January 2018

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Cloning of a T-type Ca2+ channel isoform in insulin-secreting cells

21 January 2018

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Modulation of L-type Ca2+Channels by Gβγ and Calmodulin via Interactions with N and C Termini of α1C

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Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells

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