Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice (Q28587870)

31 January 2017

title

Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice (English)

1 reference

Calcium channel, voltage-dependent, L type, alpha 1C subunit

31 January 2017

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1 reference

GOA release 2020-03-11

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17

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Verena Schulla

1

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Susanne Feil

4

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Norbert Klugbauer

15

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Robert Feil

3

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Anna Wendt

14

Anna Wendt

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Albert Salehi

Albert Salehi

13

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Mark Magnuson

Mark A. Magnuson

10

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Claes B Wollheim

16

Claes B. Wollheim

1 reference

31 January 2017

9

Ingmar Lundquist

1 reference

31 January 2017

12

Charlotta S. Olofsson

1 reference

31 January 2017

11

Stefanie Obermüller

1 reference

31 January 2017

Erik Renström

2

1 reference

31 January 2017

Isobel Franklin

5

1 reference

31 January 2017

Asllan Gjinovci

6

1 reference

31 January 2017

Xing-Jun Jing

7

1 reference

31 January 2017

Dirk Laux

8

1 reference

31 January 2017

Franz Hofmann

18

1 reference

31 January 2017

language of work or name

English

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publication date

1 August 2003

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31 January 2017

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31 January 2017

volume

22

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31 January 2017

issue

15

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31 January 2017

page(s)

3844–3854

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Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion

31 January 2017

cites work

1 reference

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A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Functional coupling between 'R-type' Ca2+ channels and insulin secretion in the insulinoma cell line INS-1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

17 March 2017

1 reference

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Electrophysiology of the pancreatic beta-cell

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Genetic approaches to the molecular understanding of type 2 diabetes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Reduction of insulin secretion in the insulinoma cell line INS-1 by overexpression of a Ca(v)2.3 (alpha1E) calcium channel antisense cassette

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Modulation of L-type Ca(2+) channels by distinct domains within SNAP-25.

29 September 2017

1 reference

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Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Mitochondrial function in normal and diabetic beta-cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians

29 September 2017

1 reference

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Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Multiple exocytotic pathways in pancreatic beta cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Potassium permeability activated by intracellular calcium ion concentration in the pancreatic beta-cell

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Gastrectomy induces impaired insulin and glucagon secretion: evidence for a gastro-insular axis in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Annexin-mediated Ca2+ influx regulates growth plate chondrocyte maturation and apoptosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Down-regulated expression of exocytotic proteins in pancreatic islets of diabetic GK rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca2+ currents in mouse pancreatic B-cells towards negative potentials

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Pima Diabetes Genes Group.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=169062

Contribution of Known and Unknown Susceptibility Genes to Early-Onset Diabetes in Scandinavia: Evidence for Heterogeneity

27 November 2018

1 reference

12 December 2020

Effects of divalent cations on beta-cell electrical activity

1 reference

12 December 2020

Bursting electrical activity in pancreatic ?-cells: evidence that the channel underlying the burst is sensitive to Ca2+ influx through L-type Ca2+ channels

1 reference

12 December 2020

U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study Group

1 reference

12 December 2020

Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization

1 reference

12 December 2020

G protein-dependent inhibition of L-type Ca2+ currents by acetylcholine in mouse pancreatic B-cells

1 reference

12 December 2020

Rapid ATP-Dependent Priming of Secretory Granules Precedes Ca2+-Induced Exocytosis in Mouse Pancreatic B-Cells

1 reference

12 December 2020

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

1 reference

12 December 2020

A Gene Conferring Susceptibility to Type 2 Diabetes in Conjunction With Obesity Is Located on Chromosome 18p11

1 reference

12 December 2020

Single nucleotide polymorphism (D68D, T to C) in the syntaxin 1A gene correlates to age at onset and insulin requirement in Type II diabetic patients

1 reference

12 December 2020

Identifiers

1 reference

31 January 2017

0 references

1 reference