Neurotrophin signal transduction in the nervous system (Q27876223)

Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons

PubMed

volume

10

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page(s)

381-91

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issue

3

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

In sympathetic but not sensory neurones, phosphoinositide-3 kinase is important for NGF-dependent survival and the retrograde transport of 125I-betaNGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The PI3K-PDK1 connection: more than just a road to PKB

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Extracellular-signal-regulated kinase signalling in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Retinal ganglion cells lose trophic responsiveness after axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

CREB is a regulatory target for the protein kinase Akt/PKB

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neurotrophins: the biological paradox of survival factors eliciting apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Induction of apoptosis by the low-affinity NGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor (NGF) induces motoneuron apoptosis in rat embryonic spinal cord in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neuronal cell death: retraction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p75NTR and the concept of cellular dependence: seeing how the other half die.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neuronal life and death decisions functional antagonism between the Trk and p75 neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p75NTR: A study in contrasts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p53-dependent cell cycle control: response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Association of the p75 neurotrophin receptor with TRAF6

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p75 neurotrophin receptor expression on adult human oligodendrocytes: signaling without cell death in response to NGF

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The anti-p75 antibody, MC192, and brain-derived neurotrophic factor inhibit nerve growth factor-dependent neurite growth from adult sensory neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Dependence on p75 for innervation of some sympathetic targets.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Elevation of ceramide within distal neurites inhibits neurite growth in cultured rat sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Inactivation of Rho signaling pathway promotes CNS axon regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Signalling through the neurotrophin receptor p75NTR.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Nerve growth factor and its low-affinity receptor promote Schwann cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Improved survival of injured sciatic nerve Schwann cells in mice lacking the p75 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Signal transduction by the neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Identification and characterization of novel substrates of Trk receptors in developing neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The small GTP-binding protein Cdc42 is required for nerve growth factor withdrawal-induced neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900092-1

7 January 2021