A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside. (Q42536958)

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scientific article published on January 1999

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English	A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.	scientific article published on January 1999

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scholarly article

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8 December 2019

A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside (English)

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8 December 2019

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apoptotic process

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C N Anderson

1

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8 December 2019

A M Tolkovsky

2

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8 December 2019

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1 January 1999

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8 December 2019

Journal of Neuroscience

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8 December 2019

19

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8 December 2019

664-673

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8 December 2019

2

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8 December 2019

NGF-mediated survival depends on p21ras in chick sympathetic neurons from the superior cervical but not from lumbosacral ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones.

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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53 Long-term culture of dissociated sympathetic neurons

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons.

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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p53, the cellular gatekeeper for growth and division

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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A synthetic inhibitor of the mitogen-activated protein kinase cascade

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Ara-C: cellular and molecular pharmacology

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Apoptosis is induced in post-mitotic rat sympathetic neurons by arabinosides and topoisomerase II inhibitors in the presence of NGF

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Specific TrkA survival signals interfere with different apoptotic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Intracellular signaling pathways activated by neurotrophic factors

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Cytosine arabinoside is neurotoxic to chick embryo spinal cord motoneurons in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Reactive oxygen species are downstream mediators of p53-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Nerve Growth Factor is Required for Induction of c-Fos Immunoreactivity by Serum, Depolarization, Cyclic AMP or Trauma in Cultured Rat Sympathetic Neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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p53 protein in sympathetic neurons: cytoplasmic localization and no apparent function in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Suppression of Fas/APO-1-mediated apoptosis by mitogen-activated kinase signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Generation of reactive oxygen intermediates after treatment of blasts of acute myeloblastic leukemia with cytosine arabinoside: role of bcl-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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A model for p53-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p44 and p42 MAP kinases is not essential for the survival of rat sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosine arabinoside induces apoptosis in cerebellar neurons in culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and isolation of proteolytically modified nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

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Cytarabine and neurologic toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9880587

12 December 2020

based on heuristic

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Identifiers

10.1523/JNEUROSCI.19-02-00664.1999

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9880587%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9880587%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9880587%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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