The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response (Q27933479)

A hybrid protein kinase-RNase in an interferon-induced pathway?

GOA release 2020-03-11

author name string

C Sidrauski

series ordinal

1

0 references

P Walter

series ordinal

2

0 references

language of work or name

English

0 references

publication date

19 September 1997

0 references

1 reference

1 December 2016

90

0 references

page(s)

1031-9

0 references

issue

6

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

The subnuclear localization of tRNA ligase in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

2-5A-dependent RNase molecules dimerize during activation by 2-5A.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Assembly of a tRNA splicing complex: evidence for concerted excision and joining steps in splicing in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Mechanism of action of a yeast RNA ligase in tRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Substrate recognition and identification of splice sites by the tRNA-splicing endonuclease and ligase from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Properties of H. volcanii tRNA intron endonuclease reveal a relationship between the archaeal and eucaryal tRNA intron processing systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Site selection by the tRNA splicing endonuclease of Xenopus laevis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

The cellular response to unfolded proteins: intercompartmental signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Saccharomyces cerevisiae IRE2/HAC1 is involved in IRE1-mediated KAR2 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

In vivo pre-tRNA processing in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Substrate recognition and splice site determination in yeast tRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

The unfolded-protein-response pathway in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

A kinase that responds to stress

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021

Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980369-4

7 January 2021