Amino acid deprivation inhibits TORC1 through a GTPase-activating protein complex for the Rag family GTPase Gtr1. (Q27937703)

Mtc5p YDR128W

1 reference

Rtc1p YOL138C

1 reference

GTPase-activating protein IML1 YJR138W

1 reference

Rag GTPase GTR1 YML121W

1 reference

Nitrogen permease regulating protein NPR2 YEL062W

1 reference

Gtr2p YGR163W

1 reference

Sea4p YBL104C

1 reference

mTOR: from growth signal integration to cancer, diabetes and ageing

author

Claudio De Virgilio

series ordinal

3

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author name string

Nicolas Panchaud

series ordinal

1

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Marie-Pierre Péli-Gulli

series ordinal

2

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language of work or name

English

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publication date

28 May 2013

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1 reference

1 December 2016

6

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page(s)

ra42

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issue

277

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cites work

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2004112

The Vam6 GEF controls TORC1 by activating the EGO complex

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2004112

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

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1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2004112

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2004112

Leucyl-tRNA synthetase controls TORC1 via the EGO complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2004112

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

21 April 2017

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A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex

21 April 2017

1 reference

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A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae

21 April 2017

1 reference

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Selective regulation of autophagy by the Iml1-Npr2-Npr3 complex in the absence of nitrogen starvation

21 April 2017

1 reference

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The TOR and EGO protein complexes orchestrate microautophagy in yeast

21 April 2017

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Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

21 April 2017

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The p85alpha subunit of phosphatidylinositol 3'-kinase binds to and stimulates the GTPase activity of Rab proteins

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2004112

TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0.

21 April 2017

1 reference

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Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

21 April 2017

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New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

21 April 2017

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Synchronizing nuclear import of ribosomal proteins with ribosome assembly

21 April 2017

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Multifunctional yeast high-copy-number shuttle vectors

21 April 2017

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Regulation of TORC1 by Rag GTPases in nutrient response

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004112

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004112

Translational regulation of GCN4 and the general amino acid control of yeast

21 April 2017

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TOR signaling in invertebrates

21 April 2017

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The essence of yeast quiescence

21 January 2018

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Target of rapamycin (TOR) in nutrient signaling and growth control

21 January 2018

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The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast

21 January 2018

1 reference

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Structure-function relationships of the G domain, a canonical switch motif

21 January 2018

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GTPase-activating proteins: helping hands to complement an active site.

21 January 2018

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Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004112

Complex chromosome 22 rearrangements in astrocytic tumors identified using microsatellite and chromosome 22 tile path array analysis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004112