NTRK gene fusions as novel targets of cancer therapy across multiple tumour types (Q28066821)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

review article

1 reference

title

NTRK gene fusions as novel targets of cancer therapy across multiple tumour types (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

author

Andrea Sartore-Bianchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

A Amatu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Salvatore Siena

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

author name string

Alessio Amatu

1

1 reference

Crossref

language of work or name

1 reference

18 March 2016

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

volume

1

2 references

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27 March 2020

issue

2

2 references

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27 March 2020

page(s)

e000023

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2

27 March 2020

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An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101

20 March 2017

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TRKing down an old oncogene in a new era of targeted therapy

20 March 2017

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A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

20 March 2017

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Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization

20 March 2017

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Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2)

20 March 2017

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A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

20 March 2017

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trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

20 March 2017

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Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma

20 March 2017

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Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer

29 September 2017

1 reference

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Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer

29 September 2017

1 reference

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Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer.

29 September 2017

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Entrectinib: a potent new TRK, ROS1, and ALK inhibitor

29 September 2017

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Chromosomal rearrangements involving the NTRK1 gene in colorectal carcinoma

29 September 2017

1 reference

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The emerging complexity of gene fusions in cancer

29 September 2017

1 reference

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Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors

29 September 2017

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Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

29 September 2017

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The landscape of kinase fusions in cancer

29 September 2017

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National Cancer Institute's Precision Medicine Initiatives for the new National Clinical Trials Network

29 September 2017

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The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

29 September 2017

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New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing

29 September 2017

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Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data

29 September 2017

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Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers.

29 September 2017

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29 September 2017

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TrkB inhibition as a therapeutic target for CNS-related disorders.

29 September 2017

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Rearrangements of NTRK1 gene in papillary thyroid carcinoma.

29 September 2017

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Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia

29 September 2017

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Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

29 September 2017

1 reference

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Congenital insensitivity to pain with anhidrosis (CIPA): novel mutations of the TRKA (NTRK1) gene, a putative uniparental disomy, and a linkage of the mutant TRKA and PKLR genes in a family with CIPA and pyruvate kinase deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070277

Trk receptor tyrosine kinases: a bridge between cancer and neural development

29 September 2017

1 reference

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Congenital insensitivity to pain with anhidrosis: novel mutations in the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070277

Rapid physical mapping of the human trk protooncogene (NTRK1) to human chromosome 1q21-q22 by P1 clone selection, fluorescence in situ hybridization (FISH), and computer-assisted microscopy

29 September 2017

1 reference

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RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features.

29 September 2017

1 reference

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Low frequency of rearrangements of the ret and trk proto-oncogenes in Japanese thyroid papillary carcinomas

2 June 2018

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Anchored multiplex PCR for targeted next-generation sequencing.

20 June 2018

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Low prevalence of RET rearrangements (RET/PTC1, RET/PTC2, RET/PTC3, and ELKS-RET) in sporadic papillary thyroid carcinomas in Taiwan Chinese

27 November 2018

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Ret and trk proto-oncogene activation in thyroid papillary carcinomas in French patients from the Champagne-Ardenne region

27 November 2018

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High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma

27 November 2018

1 reference

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1136/ESMOOPEN-2015-000023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27843590%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

2 references