The integrated landscape of driver genomic alterations in glioblastoma (Q37237987)

19 August 2017

The integrated landscape of driver genomic alterations in glioblastoma (English)

1 reference

19 August 2017

Pietro Zoppoli

9

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Serena Pellegatta

object named as

Serena Pellegatta

14

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Raul Rabadan

28

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Gilbert G Privé

object named as

Gilbert G Privé

25

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Darell D. Bigner

26

object named as

Darell D Bigner

1 reference

19 August 2017

20

Roger E McLendon

1 reference

19 August 2017

24

Tom Mikkelsen

1 reference

19 August 2017

23

Gaetano Finocchiaro

1 reference

19 August 2017

Veronique Frattini

1

1 reference

19 August 2017

Vladimir Trifonov

2

1 reference

19 August 2017

Joseph Minhow Chan

3

1 reference

19 August 2017

Angelica Castano

4

1 reference

19 August 2017

Marie Lia

5

1 reference

19 August 2017

Francesco Abate

6

1 reference

19 August 2017

Stephen T Keir

7

1 reference

19 August 2017

Alan X Ji

8

1 reference

19 August 2017

Francesco Niola

10

1 reference

19 August 2017

Carla Danussi

11

1 reference

19 August 2017

Paola Porrati

13

1 reference

19 August 2017

Adriana Heguy

15

1 reference

19 August 2017

Gaurav Gupta

16

1 reference

19 August 2017

David J Pisapia

17

1 reference

19 August 2017

Peter Canoll

18

1 reference

19 August 2017

Jeffrey N Bruce

19

1 reference

19 August 2017

Hai Yan

21

1 reference

19 August 2017

Ken Aldape

22

1 reference

19 August 2017

Anna Lasorella

27

1 reference

19 August 2017

Antonio Iavarone

29

1 reference

19 August 2017

language of work or name

English

0 references

publication date

5 August 2013

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19 August 2017

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19 August 2017

45

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19 August 2017

10

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19 August 2017

1141-1149

1 reference

Crystal structure of KLHL3 in complex with Cullin3

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Mutation of HERC2 causes developmental delay with Angelman-like features.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Transforming fusions of FGFR and TACC genes in human glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Glioblastoma: therapeutic challenges, what lies ahead

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Emerging insights into the molecular and cellular basis of glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

A novel retinoblastoma therapy from genomic and epigenetic analyses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Global identification of modular cullin-RING ligase substrates

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Chromosomal aberrations in solid tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Chemokine receptor CXCR3 promotes growth of glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Prevalence estimates for primary brain tumors in the United States by age, gender, behavior, and histology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

The landscape of somatic copy-number alteration across human cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

The transcriptional network for mesenchymal transformation of brain tumours.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Mutation patterns in cancer genomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Delta-catenin regulates spine and synapse morphogenesis and function in hippocampal neurons during development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Role of the transcriptional corepressor Bcor in embryonic stem cell differentiation and early embryonic development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

An integrated genomic analysis of human glioblastoma multiforme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Characterization of Bcor expression in mouse development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Oncogenic rearrangements of the NTRK1/NGF receptor.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Sequence and structural analysis of BTB domain proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Delta-catenin at the synaptic-adherens junction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Defective forebrain development in mice lacking gp330/megalin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

A delta-catenin signaling pathway leading to dendritic protrusions

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799953

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

3 September 2018

1 reference

BRAF mutations in hairy-cell leukemia

21 January 2018

1 reference

ChimeraScan: a tool for identifying chimeric transcription in sequencing data

21 January 2018

1 reference

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

21 January 2018

1 reference

genenames.org: the HGNC resources in 2011.

21 January 2018

1 reference

The variant call format and VCFtools

21 January 2018

1 reference

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

Protein homology detection by HMM-HMM comparison

21 January 2018

1 reference

I-TASSER: a unified platform for automated protein structure and function prediction

21 January 2018

1 reference

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

21 January 2018

1 reference

Beta propellers: structural rigidity and functional diversity

21 January 2018

1 reference

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon

21 January 2018

1 reference

Id proteins synchronize stemness and anchorage to the niche of neural stem cells

21 January 2018

1 reference

Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis

21 January 2018

1 reference

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

21 January 2018

1 reference

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NG.2734

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

23917401

1 reference