PCSK9 inhibitors and cardiovascular disease: heralding a new therapeutic era (Q28073656)

Crossref

Jane K. Stock

series ordinal

2

1 reference

Crossref

Henry N. Ginsberg

series ordinal

3

1 reference

Crossref

language of work or name

1 reference

December 2015

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Current Opinion in Lipidology

1 December 2015

3 references

17 June 2019

28 September 2019

2 October 2019

4 references

17 June 2019

28 September 2019

2 October 2019

26

1 reference

page(s)

511-20

1 reference

issue

6

1 reference

A century of cholesterol and coronaries: from plaques to genes to statins

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Do statins impair cognition? A systematic review and meta-analysis of randomized controlled trials

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PCSK9: a key modulator of cardiovascular health

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20 March 2017

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The Central Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Septic Pathogen Lipid Transport and Clearance

29 September 2017

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Safety and efficacy of anti-PCSK9 antibodies: a meta-analysis of 25 randomized, controlled trials

29 September 2017

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The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis

29 September 2017

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29 September 2017

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Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

29 September 2017

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PCSK9 inhibitors and neurocognitive adverse events: exploring the FDA directive and a proposal for N-of-1 trials

29 September 2017

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Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis

29 September 2017

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29 September 2017

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Results of bococizumab, a monoclonal antibody against proprotein convertase subtilisin/kexin type 9, from a randomized, placebo-controlled, dose-ranging study in statin-treated subjects with hypercholesterolemia

29 September 2017

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29 September 2017

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29 September 2017

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Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

29 September 2017

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PCSK9 is a critical regulator of the innate immune response and septic shock outcome.

29 September 2017

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29 September 2017

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29 September 2017

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Living the PCSK9 adventure: from the identification of a new gene in familial hypercholesterolemia towards a potential new class of anticholesterol drugs

29 September 2017

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29 September 2017

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29 September 2017

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IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor

29 September 2017

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Lipoprotein(a): resurrected by genetics

29 September 2017

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29 September 2017

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Plasma PCSK9 levels are significantly modified by statins and fibrates in humans

29 September 2017

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29 September 2017

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PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial

27 November 2018

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Anti-PCSK9 antibody effectively lowers cholesterol in patients with statin intolerance: the GAUSS-2 randomized, placebo-controlled phase 3 clinical trial of evolocumab.

27 November 2018

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A 52-week placebo-controlled trial of evolocumab in hyperlipidemia

27 November 2018

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Improvement in LDL-cholesterol levels of patients with familial hypercholesterolemia: Can we do better? Analysis of results obtained during the past two decades in 1669 French subjects

27 November 2018

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Reduction in lipoprotein(a) with PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of more than 1,300 patients in 4 phase II trials.

27 November 2018

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Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population.

27 November 2018

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Effect of the proprotein convertase subtilisin/kexin 9 monoclonal antibody, AMG 145, in homozygous familial hypercholesterolemia

27 November 2018

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Efficacy and safety of evolocumab (AMG 145), a fully human monoclonal antibody to PCSK9, in hyperlipidaemic patients on various background lipid therapies: pooled analysis of 1359 patients in four phase 2 trials

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12 December 2020

Elevated plasma PCSK9 level is equally detrimental for patients with nonfamilial hypercholesterolemia and heterozygous familial hypercholesterolemia, irrespective of low-density lipoprotein receptor defects

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12 December 2020

Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: The ODYSSEY ALTERNATIVE randomized trial

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12 December 2020

Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial

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12 December 2020

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

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12 December 2020

Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 with alirocumab

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12 December 2020

PCSK9 R46L, lower LDL, and cardiovascular disease risk in familial hypercholesterolemia: a cross-sectional cohort study

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12 December 2020

Familial hypercholesterolaemia: PCSK9 inhibitors are coming

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12 December 2020