Recent advances in understanding hepatic drug transport (Q28077066)

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Bruno Hagenbuch

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2

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Crossref

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6 October 2016

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5

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2465

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Creative Commons Attribution 4.0 International

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6 October 2016

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April 2022 Public Data File from Crossref

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Characterization of cognitive impairments and neurotransmitter changes in a novel transgenic mouse lacking Slc10a4

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29 September 2017

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PET Tracers To Study Clinically Relevant Hepatic Transporters

29 September 2017

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Molecular Imaging of Membrane Transporters' Activity in Cancer: a Picture is Worth a Thousand Tubes

29 September 2017

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Unstirred Water Layers and the Kinetics of Organic Cation Transport

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Role of (drug) transporters in imaging in health and disease

29 September 2017

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The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity

29 September 2017

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Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved

29 September 2017

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29 September 2017

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ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

29 September 2017

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Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics.

29 September 2017

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Chronic cholestatic liver diseases: clues from histopathology for pathogenesis.

29 September 2017

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Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17β-glucuronide, estrone-3-sulfate, and sulfobromophthalein

29 September 2017

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Mapping the functional yeast ABC transporter interactome

29 September 2017

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Transporters and drug-drug interactions: important determinants of drug disposition and effects

29 September 2017

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Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions.

29 September 2017

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Variability in P-glycoprotein inhibitory potency (IC₅₀) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment decision criteria.

29 September 2017

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SLC10A4 is a protease-activated transporter that transports bile acids.

29 September 2017

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In vitro methods to support transporter evaluation in drug discovery and development

29 September 2017

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Emerging transporters of clinical importance: an update from the International Transporter Consortium

29 September 2017

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The SLCO (former SLC21) superfamily of transporters

29 September 2017

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The solute carrier family 10 (SLC10): beyond bile acid transport

29 September 2017

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The ABCs of membrane transporters in health and disease (SLC series): introduction

29 September 2017

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Physiological and biochemical basis of clinical liver function tests: a review

29 September 2017

1 reference

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[N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function: radiosynthesis and proof-of-concept studies in pigs

29 September 2017

1 reference

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Highly expressed SLC35F2 in non-small cell lung cancer is associated with pathological staging

29 September 2017

1 reference

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Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only

29 September 2017

1 reference

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Quantitative targeted absolute proteomics-based ADME research as a new path to drug discovery and development: methodology, advantages, strategy, and prospects.

29 September 2017

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The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation

29 September 2017

1 reference

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In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy

29 September 2017

1 reference

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(99m)Tc-mebrofenin hepatobiliary scintigraphy with SPECT for the assessment of hepatic function and liver functional volume before partial hepatectomy

29 September 2017

1 reference

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New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

29 September 2017

1 reference

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Cloning and molecular characterization of the orphan carrier protein Slc10a4: expression in cholinergic neurons of the rat central nervous system

29 September 2017

1 reference

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Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer.

29 September 2017

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Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

29 September 2017

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Enzyme-enzyme interactions as modulators of the metabolic flux through the citric acid cycle

29 September 2017

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Enzyme-enzyme interactions and their metabolic role

29 September 2017

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Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models

29 September 2017

1 reference

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Membrane Yeast Two-Hybrid (MYTH) Mapping of Full-Length Membrane Protein Interactions.

27 November 2018

1 reference

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Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions

27 November 2018

1 reference

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Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy

27 November 2018

1 reference

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SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis

27 November 2018

1 reference

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ITC commentary on the prediction of digoxin clinical drug-drug interactions from in vitro transporter assays

27 November 2018

1 reference

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ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.

27 November 2018

1 reference

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PET imaging-based evaluation of hepatobiliary transport in humans with (15R)-11C-TIC-Me.

27 November 2018

1 reference

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The emerging role of transport systems in liver function tests.

27 November 2018

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Toward a total and regional scintigraphic liver function test enabling assessment of future remnant liver function.

27 November 2018

1 reference

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Model analysis of the concentration-dependent permeability of P-gp substrates

27 November 2018

1 reference

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Does the absence of ABCC6 (multidrug resistance protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?

27 November 2018

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Inhibitory and inductive effects of rifampin on the pharmacokinetics of bosentan in healthy subjects.

27 November 2018

1 reference

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Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

27 November 2018

1 reference

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Identification of novel genes regulated in the developing human ventral mesencephalon

27 November 2018

1 reference

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Cholylsarcosine, a new bile acid analogue: Metabolism and effect on biliary secretion in humans

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5054808

Role of Transporters in Drug Development

27 November 2018

1 reference

12 December 2020

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

1 reference

12 December 2020

Expression and localization of the uptake transporters OATP2B1, OATP3A1 and OATP5A1 in non-malignant and malignant breast tissue

1 reference

12 December 2020

Homo- and hetero-dimeric architecture of the human liver Na⁺-dependent taurocholate co-transporting protein

1 reference

12 December 2020

10.12688/F1000RESEARCH.9466.1

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

27781095

1 reference