A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination (Q28115483)

GOA release 2020-03-11

author

Agata Smogorzewska

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Anderson T Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Heather Zierhut

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Arleen D. Auerbach

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

11

Avinash Abhyankar

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Taeho Kim

2

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Henrik Molina

7

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

John E Wagner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Brooke A Conti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Francis P Lach

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Athena L Huang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Erica M Sanborn

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Belinda K Cornes

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Carrie Sougnez

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Stacey B Gabriel

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Stephen C Kowalczykowski

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

1 reference

6 August 2015

1 reference

3 January 2017

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

59

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

478-490

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

3

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

31 May 2020

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Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions

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The Rad51 paralog Rad51B promotes homologous recombinational repair

20 March 2017

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

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Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

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Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

20 March 2017

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Mechanism and regulation of incisions during DNA interstrand cross-link repair

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Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

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XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4

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20 March 2017

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Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia

20 March 2017

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Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia

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Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

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Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

20 March 2017

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20 March 2017

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A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 protein

20 March 2017

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Biallelic inactivation of BRCA2 in Fanconi anemia

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7 April 2017

1 reference

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7 April 2017

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Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia

7 April 2017

1 reference

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29 September 2017

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Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

29 September 2017

1 reference

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29 September 2017

1 reference

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FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

29 September 2017

1 reference

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RAD51 haploinsufficiency causes congenital mirror movements in humans

29 September 2017

1 reference

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Hereditary ovarian cancer: beyond the usual suspects

29 September 2017

1 reference

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Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.

29 September 2017

1 reference

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Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair

29 September 2017

1 reference

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

29 September 2017

1 reference

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Mechanism of RAD51-dependent DNA interstrand cross-link repair.

29 September 2017

1 reference

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

29 September 2017

1 reference

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Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

29 September 2017

1 reference

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

29 September 2017

1 reference

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Fanconi anemia and its diagnosis

29 September 2017

1 reference

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Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder

29 September 2017

1 reference

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Mechanism of replication-coupled DNA interstrand crosslink repair

29 September 2017

1 reference

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A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex

29 September 2017

1 reference

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Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

29 September 2017

1 reference

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

29 September 2017

1 reference

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RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.

29 September 2017

1 reference

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Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2.

29 September 2017

1 reference

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The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants

29 September 2017

1 reference

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DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links.

29 September 2017

1 reference

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Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

29 September 2017

1 reference

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The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

2 June 2018

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Corrected structure of mirin, a small-molecule inhibitor of the Mre11-Rad50-Nbs1 complex

2 June 2018

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2 June 2018

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2 June 2018

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RAD51 deficiency disrupts the corticospinal lateralization of motor control

27 November 2018

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Mutation of the RAD51C gene in a Fanconi anemia-like disorder

27 November 2018

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Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function

27 November 2018

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Negative co-dominant inhibition of recA protein function. Biochemical properties of the recA1, recA13 and recA56 proteins and the effect of recA56 protein on the activities of the wild-type recA protein function in vitro

27 November 2018

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Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26253028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biochemical events essential to the recombination activity of Escherichia coli RecA protein. II. Co-dominant effects of RecA142 protein on wild-type RecA protein function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26253028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2015.07.009

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253028%20AND%20SRC:MED&resulttype=core&format=json