Gemin5-snRNA interaction reveals an RNA binding function for WD repeat domains (Q28117609)

Nature Structural & Molecular Biology

GOA release 2020-03-11

author name string

Chi-kong Lau

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1

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4 January 2017

Jennifer L. Bachorik

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2

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4 January 2017

Gideon Dreyfuss

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3

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4 January 2017

1 May 2009

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4 January 2017

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4 January 2017

16

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4 January 2017

486–491

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4 January 2017

5

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4 January 2017

The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

1 reference

Spliceosomal UsnRNP biogenesis, structure and function

21 April 2017

1 reference

Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly

21 April 2017

1 reference

The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

21 April 2017

1 reference

Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems

21 April 2017

1 reference

Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli

21 April 2017

1 reference

Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex

21 April 2017

1 reference

Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins

21 April 2017

1 reference

Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component

21 April 2017

1 reference

Unrip is a component of SMN complexes active in snRNP assembly

21 April 2017

1 reference

Why do cells need an assembly machine for RNA-protein complexes?

21 April 2017

1 reference

The Gemin5 protein of the SMN complex identifies snRNAs

21 April 2017

1 reference

RNA-binding proteins: modular design for efficient function

21 April 2017

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Conserved structures and diversity of functions of RNA-binding proteins

21 April 2017

1 reference

The ancient regulatory-protein family of WD-repeat proteins

21 April 2017

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The WD repeat: a common architecture for diverse functions

21 April 2017

1 reference

Web services at the European bioinformatics institute

21 April 2017

1 reference

Vaults and telomerase share a common subunit, TEP1

21 April 2017

1 reference

Interaction of the U3-55k protein with U3 snoRNA is mediated by the box B/C motif of U3 and the WD repeats of U3-55k

21 April 2017

1 reference

The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization

21 April 2017

1 reference

Enhanced genome annotation using structural profiles in the program 3D-PSSM

21 April 2017

1 reference

Identification and characterization of a spinal muscular atrophy-determining gene

21 April 2017

1 reference

Essential role for the SMN complex in the specificity of snRNP assembly

21 April 2017

1 reference

A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs

21 January 2018

1 reference

Correlation between severity and SMN protein level in spinal muscular atrophy

21 January 2018

1 reference

The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy

21 January 2018

1 reference

SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing

21 January 2018

1 reference

Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs

21 January 2018

1 reference

Splicing double: insights from the second spliceosome

21 January 2018

1 reference

snRNAs contain specific SMN-binding domains that are essential for snRNP assembly

21 January 2018

1 reference

WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases

21 January 2018

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Early organization of pre-mRNA during spliceosome assembly.

21 January 2018

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Protein-protein interactions mapped by artificial proteases: where sigma factors bind to RNA polymerase

21 January 2018

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Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments

21 January 2018

1 reference

The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro

21 January 2018

1 reference

Sequence-specific interaction of U1 snRNA with the SMN complex

21 January 2018

1 reference

Directed hydroxyl radical probing of 16S rRNA in the ribosome: spatial proximity of RNA elements of the 3' and 5' domains

21 January 2018

1 reference

GRASP2: visualization, surface properties, and electrostatics of macromolecular structures and sequences

21 January 2018

1 reference

The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19377484