Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia (Q28118972)

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scientific article published on November 1, 1992

Language	Label	Description	Also known as
English	Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia	scientific article published on November 1, 1992

Statements

scholarly article

1 reference

4 January 2017

Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia (English)

1 reference

4 January 2017

Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia (English)

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1438206

26 September 2022

Integrin subunit beta 3

1 reference

GOA release 2020-03-11

blood coagulation

1 reference

GOA release 2020-03-11

platelet activation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1438206

26 September 2022

Dominique Pidard

3

object named as

D. Pidard

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1438206

26 September 2022

author name string

Y. P. Chen

1

1 reference

4 January 2017

I. Djaffar

2

1 reference

4 January 2017

B. Steiner

4

1 reference

4 January 2017

A. M. Cieutat

5

1 reference

4 January 2017

J. P. Caen

6

1 reference

4 January 2017

J. P. Rosa

7

1 reference

4 January 2017

language of work or name

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publication date

1 November 1992

1 reference

4 January 2017

full work available at URL

https://europepmc.org/articles/PMC50299

online access status

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Europe PubMed Central

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1438206

26 September 2022

https://europepmc.org/articles/PMC50299?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1438206

26 September 2022

Proceedings of the National Academy of Sciences of the United States of America

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4 January 2017

89

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4 January 2017

21

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4 January 2017

10169–10173

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4 January 2017

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1 reference

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20 March 2017

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

20 March 2017

Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors

1 reference

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20 March 2017

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

20 March 2017

Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

A variant of Glanzmann's thrombasthenia with abnormal glycoprotein IIb-IIIa complexes in the platelet membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to "integrin".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

A Taq 1 polymorphism for the human platelet glycoprotein IIIa gene (GP3A).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

The platelet membrane glycoprotein IIb-IIIa complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

The genomic organization of platelet glycoprotein IIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Glanzmann's thrombasthenia: the spectrum of clinical disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Exposure of platelet fibrinogen receptors by ADP and epinephrine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

29 September 2017

Variant of Paris-I Lariboisière thrombasthenia, a molecular anomaly of the IIb-IIIa platelet glycoprotein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Ca2+-dependent binding of a synthetic Arg-Gly-Asp (RGD) peptide to a single site on the purified platelet glycoprotein IIb-IIIa complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Glycoprotein IIIa is phosphorylated in intact human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Identification of an abnormal gene for the GPIIIa subunit of the platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Fibrinogen binding to purified platelet glycoprotein IIb-IIIa (integrin alpha IIb beta 3) is modulated by lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Regulation of glycoprotein IIB/IIIA exposure on platelets stimulated with alpha-thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Human platelets possess an inducible and saturable receptor specific for fibrinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

2 June 2018

Phosphorylation of human platelet glycoprotein IIIa (GPIIIa). Dissociation from fibrinogen receptor activation and phosphorylation of GPIIIa in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50299

27 November 2018

Activation of the fibrinogen receptor on human platelets exposed to alpha chymotrypsin. Relationship with a major proteolytic cleavage at the carboxyterminus of the membrane glycoprotein IIb heavy chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet activation and comparisons with the adenylate cyclas

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the fibrinogen receptor on human platelets by intracellular mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Paris-I-Lariboisière variant thrombasthenia. Functional disorder of human platelet aggregation, glycoprotein-independent]

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conformation-dependent epitope of human platelet glycoprotein IIIa

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative isolation of RNA from human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the mechanism of expression of secreted fibrinogen on the surface of activated human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/1438206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.89.21.10169

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1992PNAS...8910169C

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1 reference

4 January 2017

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