Experimental hemochromatosis due to MHC class I HFE deficiency: immune status and iron metabolism (Q28137777)

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S Gilfillan

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L C Kühn

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R Moret

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J B Schulze

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A Lebeau

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K Schümann

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

9 November 1999

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published in

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volume

96

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page(s)

13312-7

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issue

23

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cites work

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

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The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

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Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

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A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

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HFE gene knockout produces mouse model of hereditary hemochromatosis

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Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

20 March 2017

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Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1

20 March 2017

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Iron overload: molecular clues to its cause

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Kupffer cell staining by an HFE-specific monoclonal antibody: implications for hereditary haemochromatosis.

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Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract

29 September 2017

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Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.

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Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs

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T lymphocytes and iron overload: novel correlations of possible significance to the biology of the immunological system

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Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis

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A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA.

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Thymus-leukaemia antigens: the haemochromatosis gene product?

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13312

Population-based screening for hemochromatosis using phenotypic and DNA testing among employees of health maintenance organizations in Springfield, Missouri

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https://api.crossref.org/works/10.1073%2FPNAS.96.23.13312

An immunoassay for human transferrin

21 January 2018

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12 December 2020

Phenotypic complexity of intraepithelial lymphocytes of the small intestine

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12 December 2020

Iron overload in β2-microglobulin-deficient mice

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12 December 2020

Iron-responsive element-binding protein in hemochromatosis liver and intestine

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12 December 2020

Dietary iron levels and hypoxia independently affect iron absorption in mice

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12 December 2020

Anomalies of the CD8+ T cell pool in haemochromatosis: HLA-A3-linked expansions of CD8+CD28- T cells

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12 December 2020

Kinetic analysis of 59Fe movement across the intestinal wall in duodenal rat segments ex vivo

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12 December 2020

Shapes of MHC restriction

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12 December 2020

Iron regulatory protein as an endogenous sensor of iron in rat intestinal mucosa. Possible implications for the regulation of iron absorption

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12 December 2020

The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis

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12 December 2020

Comparison of 59Fe3+ uptake in vitro and in vivo by mouse duodenum

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12 December 2020

Identifiers

DOI

10.1073/PNAS.96.23.13312

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523544

ADS bibcode

1999PNAS...9613312B

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523544

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