c-Abl: activation and nuclear targets (Q28138395)

Cell Death & Differentiation

Europe PubMed Central

title

c-Abl: activation and nuclear targets (English)

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author name string

Y Shaul

series ordinal

1

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language of work or name

English

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publication date

January 2000

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published in

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volume

7

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issue

1

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page(s)

10-6

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cites work

Cycling, stressed-out and nervous: cellular functions of c-Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Modular binding domains in signal transduction proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFXI, a protein that binds the enhancers of several viruses and cell-cycle regulated genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Leukoregulin induction of prostaglandin-endoperoxide H synthase-2 in human orbital fibroblasts. An in vitro model for connective tissue inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

An intramolecular SH3-domain interaction regulates c-Abl activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The DNA binding domain of the human c-Abl tyrosine kinase preferentially binds to DNA sequences containing an AAC motif and to distorted DNA structures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

c-abl has a sequence-specific enhancer binding activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Src homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Regulation of Rad51 function by c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

A single HMG domain in high-mobility group 1 protein binds to DNAs as small as 20 base pairs containing the major cisplatin adduct

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

p53 and ATM: cell cycle, cell death, and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The nuclear tyrosine kinase c-Abl negatively regulates cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Three distinct signalling responses by murine fibroblasts to genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Essential roles for the Abl and Arg tyrosine kinases in neurulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

c-Abl neutralizes the inhibitory effect of Mdm2 on p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

DNA damage and cell cycle regulation of ribonucleotide reductase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Pro-apoptotic effect of the c-Abl tyrosine kinase in the cellular response to 1-beta-D-arabinofuranosylcytosine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626

7 January 2021