Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoter (Q28145110)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10967107%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoter (English)

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9 November 2019

2

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9 November 2019

author name string

S B Smith

1

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9 November 2019

D W Scheel

3

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9 November 2019

C Mrejen

4

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9 November 2019

M S German

5

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9 November 2019

language of work or name

English

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publication date

1 November 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10967107%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 November 2019

number of pages

10

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based on heuristic

inferred from page(s)

published in

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9 November 2019

volume

275

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9 November 2019

page(s)

36910-36919

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9 November 2019

issue

47

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Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

9 November 2019

cites work

1 reference

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21 January 2018

Transcribing pancreas.

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Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene

21 January 2018

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Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

21 January 2018

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Insulin-promoter-factor 1 is required for pancreas development in mice

21 January 2018

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neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

21 January 2018

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Notch signalling controls pancreatic cell differentiation

21 January 2018

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Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

21 January 2018

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Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

21 January 2018

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Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development

21 January 2018

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The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes

21 January 2018

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Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

21 January 2018

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Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13

21 January 2018

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Firefly luciferase gene: structure and expression in mammalian cells

21 January 2018

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Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding

21 January 2018

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Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations

21 January 2018

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DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

21 January 2018

1 reference

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Isolation and characterization of the human PAX4 gene

21 January 2018

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Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

21 January 2018

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Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst

21 January 2018

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Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.

21 January 2018

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Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes

21 January 2018

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21 January 2018

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Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins

21 January 2018

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Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

21 January 2018

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The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain

21 January 2018

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Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

21 January 2018

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Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance

21 January 2018

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Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a possible role of Pax4 as a transcriptional repressor in the pancreas

21 January 2018

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Inhibitory effect of pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters

21 January 2018

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A survey of 178 NF-Y binding CCAAT boxes

21 January 2018

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Individual protein-binding domains of the insulin gene enhancer positively activate beta-cell-specific transcription

21 January 2018

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Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene

21 January 2018

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Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

21 January 2018

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Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

21 January 2018

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Negative autoregulation of the organizer-specific homeobox gene goosecoid

21 January 2018

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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

21 January 2018

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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

21 January 2018

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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice

21 January 2018

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The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

21 January 2018

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Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

21 January 2018

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The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005202200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10967107%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference