ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions (Q28145238)

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scientific article (publication date: 2 June 2000)

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English	ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions	scientific article (publication date: 2 June 2000)

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828059%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions (English)

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7 November 2019

phosphorylation

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based on heuristic

inferred from title

2

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7 November 2019

Miles D. Houslay

5

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7 November 2019

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S J MacKenzie

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7 November 2019

I McPhee

3

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7 November 2019

G B Bolger

4

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7 November 2019

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publication date

1 June 2000

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7 November 2019

Journal of Biological Chemistry

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7 November 2019

275

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7 November 2019

22

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7 November 2019

16609-16617

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7 November 2019

Tailoring cAMP-signalling responses through isoform multiplicity

1 reference

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Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: a diverse family of regulatory enzymes

1 reference

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Diversity in cyclic nucleotide phosphodiesterase isoenzyme families

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Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases

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A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs

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Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase.

1 reference

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Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation

1 reference

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21 January 2018

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

1 reference

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21 January 2018

cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

1 reference

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The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

1 reference

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Inhibition by cAMP of Ras-Dependent Activation of Raf

1 reference

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21 January 2018

Negative regulation of Raf-1 by phosphorylation of serine 621.

1 reference

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21 January 2018

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

1 reference

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PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

1 reference

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The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.

1 reference

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21 January 2018

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

1 reference

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21 January 2018

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo

1 reference

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21 January 2018

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

1 reference

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21 January 2018

A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1.

1 reference

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21 January 2018

Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene

1 reference

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21 January 2018

The human cyclic AMP-specific phosphodiesterase PDE-46 (HSPDE4A4B) expressed in transfected COS7 cells occurs as both particulate and cytosolic species that exhibit distinct kinetics of inhibition by the antidepressant rolipram

1 reference

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Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes

1 reference

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21 January 2018

A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes

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Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm

1 reference

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21 January 2018

Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

1 reference

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Diversity in function and regulation of MAP kinase pathways

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Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase

1 reference

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Functional Anchoring of the cAMP-Dependent Protein Kinase

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Microtubules in the Cytoplasm of an Amoeba

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