The death effector domain protein family (Q28186582)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634625%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

The death effector domain protein family (English)

1 reference

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21 December 2019

1 reference

2

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21 December 2019

Marcus E. Peter

series ordinal

4

1 reference

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21 December 2019

author name string

Bryan C Barnhart

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634625%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Elizabeth C Alappat

series ordinal

3

1 reference

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21 December 2019

language of work or name

English

0 references

publication date

1 November 2003

1 reference

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21 December 2019

1 reference

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21 December 2019

volume

22

1 reference

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21 December 2019

issue

53

1 reference

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21 December 2019

page(s)

8634-8644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634625%20AND%20SRC:MED&resulttype=core&format=json

DEDD and DEDD2 associate with caspase-8/10 and signal cell death

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Selective expression of FLIP in malignant melanocytic skin lesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FLASH coordinates NF-kappa B activity via TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Cellular expression, developmental regulation, and phylogenic conservation of PEA-15, the astrocytic major phosphoprotein and protein kinase C substrate.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Resistance to TRAIL-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Improved artificial death switches based on caspases and FADD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

CASH, a novel caspase homologue with death effector domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Resistance to CD95-mediated apoptosis through constitutive c-FLIP expression in a non-Hodgkin's lymphoma B cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Induction of apoptosis by cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FADD gene therapy for malignant gliomas in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Apoptosis. Searching for FLASH domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Identification of a novel tumor necrosis factor-alpha-inducible gene, SCC-S2, containing the consensus sequence of a death effector domain of fas-associated death domain-like interleukin- 1beta-converting enzyme-inhibitory protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

DEDD regulates degradation of intermediate filaments during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

DEFT, a novel death effector domain-containing molecule predominantly expressed in testicular germ cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A novel single amino acid deletion caspase-8 mutant in cancer cells that lost proapoptotic activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Dimer formation drives the activation of the cell death protease caspase 9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Identification and characterization of DEDD2, a death effector domain-containing protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Caspase activation: the induced-proximity model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Casper is a FADD- and caspase-related inducer of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FADD/MORT1, a signal transducer that can promote cell death or cell growth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Regulation of Fas-associated death domain interactions by the death effector domain identified by a modified reverse two-hybrid screen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The fight of viruses against apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

A role for FADD in T cell activation and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Caspase-10 is an initiator caspase in death receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Nuclear factor-kappa B-inducible death effector domain-containing protein suppresses tumor necrosis factor-mediated apoptosis by inhibiting caspase-8 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207103

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207103

2 references

Consolidated OpenCitations Corpus – April 2017

4554122

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634625%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 December 2019

1046333962

0 references

4554122

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4554122

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634625%20AND%20SRC:MED&resulttype=core&format=json