Cytokines and acute neurodegeneration (Q28190084)

Nature Reviews Neuroscience

Europe PubMed Central

title

Cytokines and acute neurodegeneration (English)

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author name string

S M Allan

series ordinal

1

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N J Rothwell

series ordinal

2

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language of work or name

English

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publication date

October 2001

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published in

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volume

2

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page(s)

734-44

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issue

10

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cites work

Inflammation in the nervous system

1 reference

7 January 2021

Inflammatory mediators and stroke: new opportunities for novel therapeutics

1 reference

7 January 2021

Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia

1 reference

7 January 2021

Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS

1 reference

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

7 January 2021

Four new members expand the interleukin-1 superfamily

1 reference

7 January 2021

Identification and initial characterization of four novel members of the interleukin-1 family

1 reference

7 January 2021

Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2

1 reference

7 January 2021

TGF-beta in the central nervous system: potential roles in ischemic injury and neurodegenerative diseases.

1 reference

7 January 2021

Transforming growth factor-betas in neurodegenerative disease

1 reference

7 January 2021

The latent transforming growth factor beta binding protein (LTBP) family

1 reference

7 January 2021

Expression of TGF-beta type II receptor mRNA in the CNS.

1 reference

7 January 2021

Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain

1 reference

7 January 2021

Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat.

1 reference

7 January 2021

Tumor necrosis factor-alpha expression in ischemic neurons.

1 reference

7 January 2021

Concomitant cortical expression of TNF-alpha and IL-1 beta mRNAs follows early response gene expression in transient focal ischemia.

1 reference

7 January 2021

Microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression

1 reference

7 January 2021

Increased expression of TGF-beta 1 in brain tissue after ischemic stroke in humans

1 reference

7 January 2021

Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors

1 reference

7 January 2021

Cytokine-mediated neuronal apoptosis

1 reference

7 January 2021

TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures.

1 reference

7 January 2021

Mechanisms of cell death in primary cortical neurons and PC12 cells

1 reference

7 January 2021

Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats

1 reference

7 January 2021

Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

1 reference

7 January 2021

Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat.

1 reference

7 January 2021

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.

1 reference

7 January 2021

Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat

1 reference

7 January 2021

Transforming growth factor-beta 1 prevents glutamate neurotoxicity in rat neocortical cultures and protects mouse neocortex from ischemic injury in vivo.

1 reference

7 January 2021

TGF-beta 1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms.

1 reference

7 January 2021

IL-10 reduces rat brain injury following focal stroke.

1 reference

7 January 2021

Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury.

1 reference

7 January 2021

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

1 reference

7 January 2021

Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor

1 reference

7 January 2021

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1 reference

7 January 2021

Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons

1 reference

7 January 2021

Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat.

1 reference

7 January 2021

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

1 reference

7 January 2021

Inhibition of tumor necrosis factor and amelioration of brain infarction in mice

1 reference

7 January 2021

Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage.

1 reference

7 January 2021

Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.

1 reference

7 January 2021

Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury

1 reference

7 January 2021

Tumor necrosis factor(alpha) and insulin-like growth factor-I in the brain: is the whole greater than the sum of its parts?

1 reference

7 January 2021

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

1 reference

7 January 2021

Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat.

1 reference

7 January 2021

Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat.

1 reference

7 January 2021

Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain

1 reference

7 January 2021

Role of IL-1alpha and IL-1beta in ischemic brain damage.

1 reference

7 January 2021

Endogenous interleukin-1 receptor antagonist is neuroprotective

1 reference

7 January 2021

A Transforming Growth Factor-β Antagonist Unmasks the Neuroprotective Role of This Endogenous Cytokine in Excitotoxic and Ischemic Brain Injury

1 reference

7 January 2021

Astroglial overproduction of TGF-beta 1 enhances inflammatory central nervous system disease in transgenic mice .

1 reference

7 January 2021

Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice

1 reference

7 January 2021

Lack of interleukin-6 expression is not protective against focal central nervous system ischemia

1 reference

7 January 2021

Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons.

1 reference

7 January 2021

Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.

1 reference

7 January 2021

Gene expression of IL-10 in relationship to TNF-alpha, IL-1beta and IL-2 in the rat brain following middle cerebral artery occlusion.

1 reference

7 January 2021

Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation

1 reference

7 January 2021

The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat.

1 reference

7 January 2021

Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin

1 reference

7 January 2021

The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

1 reference

7 January 2021

Tissue distribution of the P2X7 receptor

1 reference

7 January 2021

TGF-beta1-dependent differential expression of a rat homolog for latent TGF-beta binding protein in astrocytes and C6 glioma cells

1 reference

7 January 2021

Induction and regulation of interleukin-6 gene expression in rat astrocytes

1 reference

7 January 2021

Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures

1 reference

7 January 2021

Interleukin-1β induction of tumor necrosis factor-alpha gene expression in human astroglioma cells

1 reference

7 January 2021

Transforming growth factor-beta 1 (TGF-β1) expression and regulation in rat cortical astrocytes

1 reference

7 January 2021

Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines

1 reference

7 January 2021

Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain

1 reference

7 January 2021

Vagotomy blocks the induction of interleukin-1beta (IL-1beta) mRNA in the brain of rats in response to systemic IL-1beta.

1 reference

7 January 2021

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury.

1 reference

7 January 2021

Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

1 reference

7 January 2021

Kainate receptor activation induces mixed lineage kinase-mediated cellular signaling cascades via post-synaptic density protein 95

1 reference

7 January 2021

Controversies surrounding glucocorticoid-mediated cell death in the hippocampus

1 reference

7 January 2021

Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning

1 reference

7 January 2021

In vivo neutralization of endogenous brain fractalkine increases hippocampal TNFalpha and 8-isoprostane production induced by intracerebroventricular injection of LPS.

1 reference

7 January 2021

Inhibition of microglial cell RANTES production by IL-10 and TGF-beta.

1 reference

7 January 2021

Reduction of inflammatory response in the mouse brain with adenoviral-mediated transforming growth factor-ss1 expression

1 reference

7 January 2021

Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat

1 reference

7 January 2021

SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia.

1 reference

7 January 2021

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

1 reference

7 January 2021

Identification and characterization of receptors for tumor necrosis factor-alpha in the brain

1 reference

7 January 2021

Interleukin-1 receptors: cloning studies and role in central nervous system disorders

1 reference

7 January 2021

Interleukin 1 in the brain: biology, pathology and therapeutic target

1 reference

7 January 2021

Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

1 reference

7 January 2021

The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense

1 reference

7 January 2021

Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components

1 reference

7 January 2021

A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation

1 reference

7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

7 January 2021

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

7 January 2021

Characteristic localization of gp130 (the signal-transducing receptor component used in common for IL-6/IL-11/CNTF/LIF/OSM) in the rat brain

1 reference

7 January 2021

Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines

1 reference

7 January 2021

Production of interleukin-10 by mouse glial cells in culture

1 reference

7 January 2021

IL-10 promotes survival of microglia without activating Akt.

1 reference

7 January 2021

RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

1 reference

7 January 2021

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

7 January 2021

Interleukin-1 beta depresses calcium currents in CA1 hippocampal neurons at pathophysiological concentrations

1 reference

7 January 2021

Interleukin-1 beta inhibits glutamate release in hippocampus of young, but not aged, rats.

1 reference

7 January 2021

Interleukin-1 beta inhibits long-term potentiation in the CA3 region of mouse hippocampal slices.

1 reference

7 January 2021

Interleukin-1 beta increases synaptic inhibition in rat hippocampal pyramidal neurons in vitro

1 reference

7 January 2021

Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: platelet-activating factor as a preferential mediator of cyclooxygenase-2 expression

1 reference

7 January 2021

Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebral ischaemia or activation of NMDA receptors in the rat brain

1 reference

7 January 2021

Evidence for the involvement of corticotrophin-releasing hormone in the pathogenesis of traumatic brain injury.

1 reference

7 January 2021

Opposite effects of TGF-beta 1 on rapidly- and slowly-triggered excitotoxic injury.

1 reference

7 January 2021

Transforming growth factor beta1 regulates the expression of cyclooxygenase in cultured cortical astrocytes and neurons.

1 reference

7 January 2021

Brain glia release factors with opposing actions upon neuronal survival.

1 reference

7 January 2021

Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

1 reference

7 January 2021

TNFalpha reduces glutamate induced intracellular Ca(2+) increase in cultured cortical astrocytes

1 reference

7 January 2021

Regulation by interleukin-1 of nerve growth factor secretion and nerve growth factor mRNA expression in rat primary astroglial cultures

1 reference

7 January 2021

Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death

1 reference

7 January 2021

Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil.

1 reference

7 January 2021

Mechanism of interleukin-1- and tumor necrosis factor alpha-dependent regulation of the alpha 1-antichymotrypsin gene in human astrocytes

1 reference

7 January 2021

Activation of the complement cascade and increase of clusterin in the brain following a cortical contusion in the adult rat.

1 reference

7 January 2021

Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta1.

1 reference

7 January 2021

Glial cell line-derived neurotrophic factor requires transforming growth factor-beta for exerting its full neurotrophic potential on peripheral and CNS neurons.

1 reference

7 January 2021

Transforming growth factor-beta1 induces apoptosis of rat microglia without relation to bcl-2 oncoprotein expression.

1 reference

7 January 2021

Molecular consequences of activated microglia in the brain: overactivation induces apoptosis.

1 reference

7 January 2021

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

1 reference

7 January 2021

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

1 reference

7 January 2021

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

1 reference

7 January 2021

An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat.

1 reference

7 January 2021

Expression of fas antigen in the normal mouse brain.

1 reference

7 January 2021

Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta-converting enzyme-mediated apoptosis

1 reference

7 January 2021

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

1 reference

7 January 2021

TGF-beta1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures

1 reference

7 January 2021

TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia.

1 reference

7 January 2021

Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization

1 reference

7 January 2021

Recombinant human interleukin-1 induces meningitis and blood-brain barrier injury in the rat. Characterization and comparison with tumor necrosis factor

1 reference

7 January 2021

The dominant role of exogenous or endogenous interleukin-1 beta on expression and activity of inducible nitric oxide synthase in rat microvascular brain endothelial cells.

1 reference

7 January 2021

Upregulation of intercellular adhesion molecule-1 (ICAM-1) expression in primary cultures of human brain microvessel endothelial cells by cytokines and lipopolysaccharide

1 reference

7 January 2021

Intracerebral administration of interleukin-1beta and induction of inflammation, apoptosis, and vasogenic edema

1 reference

7 January 2021

Cytokines and the central nervous system

1 reference

7 January 2021

Fever in acute stroke worsens prognosis. A prospective study

1 reference

7 January 2021

Cytokines and the nervous system II: Actions and mechanisms of action

1 reference

7 January 2021

Effect of selective inhibition of cyclooxygenase 2 on temporary focal cerebral ischemia in rats

1 reference

7 January 2021

Transcriptional regulation of the human interleukin 1beta gene by fibronectin: role of protein kinase C and activator protein 1 (AP-1).

1 reference

7 January 2021

Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation.

1 reference

7 January 2021

Seizure induced synthesis of fibronectin is rapid and age dependent: implications for long-term potentiation and sprouting.

1 reference

7 January 2021

Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.

1 reference

7 January 2021

Interferon-beta in multiple sclerosis: altering the balance of interleukin-12 and interleukin-10?

1 reference

7 January 2021

The safety and efficacy of interleukin-1 receptor antagonist in the treatment of rheumatoid arthritis

1 reference

7 January 2021

Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier

1 reference

7 January 2021

The role of cytokines and growth factors in seizures and their sequelae

1 reference

7 January 2021

Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice

1 reference

7 January 2021

Increased neuronal beta-amyloid precursor protein expression in human temporal lobe epilepsy: association with interleukin-1 alpha immunoreactivity

1 reference

7 January 2021

Interleukin (IL)1beta, IL-1alpha, and IL-1 receptor antagonist gene polymorphisms in patients with temporal lobe epilepsy.

1 reference

7 January 2021

Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat

1 reference

7 January 2021

Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy

1 reference

7 January 2021

Cytokine signals propagate through the brain

1 reference

7 January 2021

Identifiers

DOI

10.1038/35094583

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2648878

1044265328

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2648878

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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