Potential cardioprotective actions of no-releasing aspirin (Q28193422)

Nature Reviews Drug Discovery

Europe PubMed Central

title

Potential cardioprotective actions of no-releasing aspirin (English)

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Louis Ignarro

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2

object named as

Louis J Ignarro

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author name string

John L Wallace

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1

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language of work or name

English

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publication date

May 2002

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published in

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volume

1

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page(s)

375-82

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issue

5

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cites work

Aspirin as an antiplatelet drug

1 reference

Final report on the aspirin component of the ongoing Physicians' Health Study

21 January 2018

1 reference

Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration

21 January 2018

1 reference

Acetylation of prostaglandin synthase by aspirin

21 January 2018

1 reference

Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years

21 January 2018

1 reference

Nonsteroidal anti-inflammatory drugs and peptic ulcer disease

21 January 2018

1 reference

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

21 January 2018

1 reference

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study

21 January 2018

1 reference

Risk of cardiovascular events associated with selective COX-2 inhibitors

21 January 2018

1 reference

Effect of cyclooxygenase-2 inhibition on renal function in elderly persons receiving a low-salt diet. A randomized, controlled trial.

21 January 2018

1 reference

Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects

21 January 2018

1 reference

Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat

21 January 2018

1 reference

Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach.

21 January 2018

1 reference

Nitric oxide in mucosal defense: a little goes a long way.

21 January 2018

1 reference

Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative

21 January 2018

1 reference

Nitrosylhemoglobin, an unequivocal index of nitric oxide release from nitroaspirin: in vitro and in vivo studies in the rat by ESR spectroscopy

21 January 2018

1 reference

Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats

21 January 2018

1 reference

The effect of aspirin and two nitric oxide donors on the infarcted heart in situ

21 January 2018

1 reference

Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme.

21 January 2018

1 reference

Antiaggregating and vasodilatory effects of a new nitroderivative of acetylsalicylic acid

21 January 2018

1 reference

Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach

21 January 2018

1 reference

Antihypertensive drug therapies and the risk of ischemic stroke

21 January 2018

1 reference

Nonsteroidal anti-inflammatory drugs and antihypertensives

21 January 2018

1 reference

Nephrotoxicity of nonsteroidal anti-inflammatory drugs: physiologic foundations and clinical implications

21 January 2018

1 reference

Selective cyclo-oxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence

21 January 2018

1 reference

Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat.

21 January 2018

1 reference

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

Nitric oxide inhibits ornithine decarboxylase by S-nitrosylation

21 January 2018

1 reference

Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation

21 January 2018

1 reference

Restenosis after coronary angioplasty. Potential biologic determinants and role of intimal hyperplasia

21 January 2018

1 reference

The restenosis paradigm revisited: an alternative proposal for cellular mechanisms

21 January 2018

1 reference

21 January 2018

1 reference

Effects of nitric oxide-releasing aspirin versus aspirin on restenosis in hypercholesterolemic mice

21 January 2018

1 reference

Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis.

21 January 2018

1 reference

Reduction of gastrointestinal injury in acute endotoxic shock by flurbiprofen nitroxybutylester.

21 January 2018

1 reference

Augmented myocardial ischaemia by nicotine--mechanisms and their possible significance

21 January 2018

1 reference

Nitric oxide-releasing NSAIDs: a review of their current status

21 January 2018

1 reference

A comparison of the anti-inflammatory and anti-nociceptive activity of nitroaspirin and aspirin

21 January 2018

1 reference

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

From bench to clinic with apoptosis-based therapeutic agents

21 January 2018

1 reference

Apoptosis-based therapies

21 January 2018

1 reference

Cytokine-processing enzymes. Stopping the cuts

21 January 2018

1 reference

21 January 2018

Caspases: enemies within

1 reference

Nitrosylation. the prototypic redox-based signaling mechanism.

21 January 2018

1 reference

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

21 January 2018

1 reference

IL-1 and IL-18 receptors, and their extended family.

21 January 2018

1 reference

IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor

21 January 2018

1 reference

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

21 January 2018

1 reference

NO-releasing NSAIDs are caspase inhibitors

21 January 2018

1 reference

The effects of a novel NSAID on chronic neuroinflammation are age dependent.

21 January 2018

1 reference

On the mechanism by which vascular endothelial cells regulate their oxygen consumption

21 January 2018

1 reference

Dynamic regulation of metabolism and respiration by endogenously produced nitric oxide protects against oxidative stress

21 January 2018

1 reference

Nitric oxide-releasing NSAIDs inhibit interleukin-1beta converting enzyme-like cysteine proteases and protect endothelial cells from apoptosis induced by TNFalpha

21 January 2018

1 reference

NO-aspirin protects from T cell–mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines

21 January 2018

1 reference

Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects

21 January 2018

1 reference

Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury

31 March 2020

1 reference

Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding

31 March 2020

1 reference

Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases

31 March 2020

1 reference

A diclofenac derivative without ulcerogenic properties

31 March 2020

1 reference

Gastrointestinal-sparing anti-inflammatory drugs: The development of nitric oxide-releasing NSAIDs

31 March 2020

1 reference

Nitrosothiol esters of diclofenac: synthesis and pharmacological characterization as gastrointestinal-sparing prodrugs

31 March 2020

1 reference

NO-naproxen vs. naproxen: ulcerogenic, analgesic and anti-inflammatory effects

31 March 2020

1 reference

In Vivo Antithrombotic Effects of a Nitric Oxide-Releasing Aspirin Derivative, NCX-4016

31 March 2020

1 reference

IL-1 beta converting enzyme is a target for nitric oxide-releasing aspirin: new insights in the antiinflammatory mechanism of nitric oxide-releasing nonsteroidal antiinflammatory drugs

31 March 2020

1 reference

Prevention of pulmonary thromboembolism by NCX 4016, a nitric oxide-releasing aspirin

31 March 2020

1 reference

Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats

31 March 2020

1 reference

Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats

31 March 2020

1 reference

Selective cyclo-oxygenase-2 inhibitors: cardiovascular and gastrointestinal toxicity

31 March 2020

1 reference

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

31 March 2020

1 reference

Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: implications for the regulation of nitric oxide biosynthesis by arginase

31 March 2020

1 reference

Sodium nitroprusside inhibits proliferation and putrescine synthesis in human colon carcinoma cells

31 March 2020

1 reference

A perspective on the potential problems with aspirin as an antithrombotic agent: a comparison of studies in an animal model with clinical trials

31 March 2020

1 reference

Restenosis is associated with decreased coronary artery nitric oxide synthase

31 March 2020

1 reference

Local intramural delivery of L-arginine enhances nitric oxide generation and inhibits lesion formation after balloon angioplasty

31 March 2020

1 reference

Local L-arginine delivery after balloon angioplasty reduces monocyte binding and induces apoptosis

31 March 2020

1 reference

Role of nitric oxide in restenosis after experimental balloon angioplasty in the hypercholesterolemic rabbit: effects on neointimal hyperplasia and vascular remodeling

31 March 2020

1 reference

Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate

31 March 2020

1 reference

Enhanced anti-inflammatory effects of a nitric oxide–releasing derivative of mesalamine in rats

31 March 2020

1 reference

Nitric oxide and prostacyclin influence coronary vasomotor tone in perfused rabbit heart and modulate endothelin-1 activity

31 March 2020

1 reference

Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction

31 March 2020

1 reference

Nitric oxide-releasing non-steroidal anti-inflammatory drugs: a novel approach for reducing gastrointestinal toxicity

31 March 2020

1 reference

Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice

31 March 2020

1 reference

Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

31 March 2020

1 reference