Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation (Q28193702)

2

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Carol Dangelmaier

3

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Robert T Dorsam

4

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Jianguo Jin

5

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James L Daniel

6

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Satya P Kunapuli

Glycoprotein VI-mediated platelet fibrinogen receptor activation occurs through calcium-sensitive and PKC-sensitive pathways without a requirement for secreted ADP

7

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language of work or name

English

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publication date

1 December 2002

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published in

Biochemical Journal

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volume

368

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issue

Pt 2

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page(s)

535-43

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cites work

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12 December 2020

Abnormal inside-out signal transduction-dependent activation of glycoprotein IIb-IIIa in a patient with impaired pleckstrin phosphorylation

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12 December 2020

Human platelet signaling defect characterized by impaired production of inositol-1,4,5-triphosphate and phosphatidic acid and diminished Pleckstrin phosphorylation: evidence for defective phospholipase C activation

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12 December 2020

Decreased expression of phospholipase C-beta 2 isozyme in human platelets with impaired function

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12 December 2020

Signaling through G proteins in platelets: to the integrins and beyond

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12 December 2020

Differential involvement of tyrosine and serine/threonine kinases in platelet integrin alphaIIbbeta3 exposure

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12 December 2020

Concomitant activation of Gi and Gq protein-coupled receptors does not require an increase in cytosolic calcium for platelet aggregation

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12 December 2020

Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets

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12 December 2020

Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors

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12 December 2020

Different translocation of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets

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12 December 2020

Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels

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12 December 2020

Regulation of glycoprotein IIb-IIIa receptor function studied with platelets permeabilized by the pore-forming complement proteins C5b-9

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12 December 2020

A New Protein Kinase C, nPKCη′, and nPCKθ Are Expressed in Human Platelets: Involvement of nPKCη′ and nPKCθ in Signal Transduction Stimulated by PAF

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12 December 2020

Exposure of platelet fibrinogen receptors by zinc ions: role of protein kinase C

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12 December 2020

Concomitant activation of Gi protein-coupled receptor and protein kinase C or phospholipase C is required for platelet aggregation

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12 December 2020