Age-related impairment of p56lck and ZAP-70 activities in human T lymphocytes activated through the TcR/CD3 complex (Q28199301)

1

0 references

D Gagné

2

0 references

A C Goulet

3

0 references

S Desgeorges

4

0 references

G Lacombe

5

0 references

M Arcand

6

0 references

G Dupuis

The role of CD45 and CD45-associated molecules in T cell activation

7

0 references

language of work or name

English

0 references

publication date

April 1999

0 references

published in

Experimental Gerontology

0 references

volume

34

0 references

issue

2

0 references

page(s)

197-216

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Reductions in the activation of ERK and JNK are associated with decreased IL-2 production in T cells from elderly humans stimulated by the TCR/CD3 complex and costimulatory signals

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Vav: function and regulation in hematopoietic cell signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

T cell antigen receptor signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

The T cell receptor/CD3 complex: a dynamic protein ensemble

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Purification and characterization of an activated form of the protein tyrosine kinase Lck from an Escherichia coli expression system.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Signal transduction changes in granulocytes and lymphocytes with ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Age-dependent changes in transmembrane signalling: identification of G proteins in human lymphocytes and polymorphonuclear leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Cellular distribution of protein kinase C isozymes in CD3-mediated stimulation of human T lymphocytes with aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Rapid tyrosine phosphorylation of Grb2 and Shc in T cells exposed to anti-CD3, anti-CD4, and anti-CD45 stimuli: differential effects of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Diminished activation of the MAP kinase pathway in CD3-stimulated T lymphocytes from old mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Activation of murine T-cells via phospholipase-C gamma 1-associated protein tyrosine phosphorylation is reduced with aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Free radical involvement in aging. Pathophysiology and therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Positive versus negative signaling by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Decline in Phytohemagglutinin Responsiveness of Spleen Cells from Aging Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Admission criteria for immunogerontological studies in man: the SENIEUR protocol

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Accumulation of hyporesponsive, calcium extruding memory T cells as a key feature of age-dependent immune dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

The aging immune system: primer and prospectus

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Early activation defects in T lymphocytes from aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Diminished calcium influx in lectin-stimulated T cells from old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Protein modules and signalling networks

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Diminished calcium signal generation in subsets of T lymphocytes that predominate in old mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Tyrosine-specific protein phosphorylation in response to anti-CD3 antibody is diminished in old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Altered switch in lipid composition during T-cell blast transformation in the healthy elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Differential age-change in the numbers of CD4+CD45RA+ and CD4+CD29+ T cell subsets in human peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Influence of age on the signal transduction of T cells in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Impairment of signal transduction in T cells from old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Cell surface markers, inositol phosphate levels and membrane potential of lymphocytes from young and old human patients

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Expression and catalytic activities of protein tyrosine kinases (PTKs) Fyn and Lck in peripheral blood T cells from elderly humans stimulated through the T cell receptor (TCR)/CD3 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

The aging immune system: primary and secondary alterations of immune reactivity in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2898%2900061-8

7 January 2021