Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) (Q28199570)

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3 November 2019

title

Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) (English)

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3 November 2019

1

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3 November 2019

author name string

M E Burczynski

2

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3 November 2019

J M Jez

3

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3 November 2019

H K Lin

4

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3 November 2019

H Ma

5

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3 November 2019

M Moore

6

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3 November 2019

K Ratnam

7

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3 November 2019

N Palackal

8

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3 November 2019

language of work or name

English

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publication date

1 January 2001

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Molecular and Cellular Endocrinology

3 November 2019

published in

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3 November 2019

volume

171

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3 November 2019

issue

1-2

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3 November 2019

page(s)

137-149

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17 beta-hydroxysteroid dehydrogenase: isozymes and mutations

3 November 2019

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The kinetic mechanism catalysed by homogeneous rat liver 3 alpha-hydroxysteroid dehydrogenase. Evidence for binary and ternary dead-end complexes containing non-steroidal anti-inflammatory drugs

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7 January 2021

Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+

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Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase

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Detection of a transient enzyme-steroid complex during active-site-directed irreversible inhibition of 3-oxo-delta 5-steroid isomerase

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7 January 2021

Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione

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7 January 2021

Molecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder

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7 January 2021

Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase

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7 January 2021

Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry

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Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells

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7 January 2021

Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily

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7 January 2021

Comparative anatomy of the aldo-keto reductase superfamily

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7 January 2021

Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases

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7 January 2021

The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology

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7 January 2021

Inhibition of 3(17)beta-hydroxysteroid dehydrogenase from Pseudomonas testosteroni by steroidal A ring fused pyrazoles

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7 January 2021

Expression and Characterization of Recombinant Type 2 3 -Hydroxysteroid Dehydrogenase (HSD) from Human Prostate: Demonstration of Bifunctional 3 /17 -HSD Activity and Cellular Distribution

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7 January 2021

Characterization of homogeneous recombinant rat ovarian 20alpha-hydroxysteroid dehydrogenase: fluorescent properties and inhibition profile

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7 January 2021

Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins

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7 January 2021

Molecular endocrinology of hydroxysteroid dehydrogenases

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7 January 2021

Purification and properties of a 3 alpha-hydroxysteroid dehydrogenase of rat liver cytosol and its inhibition by anti-inflammatory drugs

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7 January 2021

Clues to the development of mechanism-based inactivators of 3 alpha-hydroxysteroid dehydrogenase: comparison of steroidal and nonsteroidal Michael acceptors and epoxides

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7 January 2021

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

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7 January 2021

Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases

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7 January 2021

Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis

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7 January 2021

Statistical estimations in enzyme kinetics

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7 January 2021

10.1016/S0303-7207(00)00426-3

Identifiers

DOI

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release_elxhlqr6xrezdjhgycw3q5betq

3 November 2019

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