A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO (Q28201640)

2

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Jennifer Lewis

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Colin S Duckett

4

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Robert G Korneluk

5

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Peter Liston

Journal of Biological Chemistry

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language of work or name

English

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publication date

28 February 2003

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published in

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volume

278

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issue

9

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page(s)

7494-9

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cites work

The machinery of programmed cell death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Caspases: opening the boxes and interpreting the arrows

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Antiapoptotic proteins. The bcl-2 and inhibitor of apoptosis protein families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Reprieval from execution: the molecular basis of caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Cell death inhibition: keeping caspases in check

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Breaking the mitochondrial barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Mitochondria, the killer organelles and their weapons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Structural basis of IAP recognition by Smac/DIABLO

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Biochemical and genetic interactions between Drosophila caspases and the proapoptotic genes rpr, hid, and grim

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Molecular mechanisms of cell death and phagocytosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Drosophila sickle is a novel grim-reaper cell death activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Sequence requirements for Hid binding and apoptosis regulation in the baculovirus inhibitor of apoptosis Op-IAP. Hid binds Op-IAP in a manner similar to Smac binding of XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Death and anti-death: tumour resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Inhibitors of apoptosis proteins in prostate cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Caspases: more than just killers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200695200

21 January 2018

Identifiers

DOI

10.1074/JBC.C200695200

1 reference

Consolidated OpenCitations Corpus – April 2017

4276796

4276796

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference