The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction (Q24292709)

ubiquitin-proteasome system

Europe PubMed Central

title

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction (English)

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main subject

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proteolysis

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Proteasome 20S subunit alpha 6

inferred from title

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Ubiquitin in homeostasis, development and disease.

GOA release 2020-03-11

author

Aaron Ciechanover

series ordinal

2

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author name string

Michael H Glickman

series ordinal

1

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language of work or name

English

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publication date

April 2002

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published in

Physiological Reviews

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volume

82

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page(s)

373-428

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issue

2

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cites work

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Functional analysis of the Saccharomyces cerevisiae UBC11 gene

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Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes.

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Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519

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Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome

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Characterization of ARC, a divergent member of the AAA ATPase family from Rhodococcus erythropolis.

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Characterization of two subunits of Arabidopsis 19S proteasome regulatory complex and its possible interaction with the COP9 complex.

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A theoretical approach towards the identification of cleavage-determining amino acid motifs of the 20 S proteasome.

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RING domains: master builders of molecular scaffolds?

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An algorithm for the prediction of proteasomal cleavages

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Electron microscopy and subunit-subunit interaction studies reveal a first architecture of COP9 signalosome

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ER protein quality control and proteasome-mediated protein degradation

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Endoplasmic reticulum-associated protein degradation

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Getting in and out of the proteasome

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Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

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Subunits of the regulatory complex of the 26S protease

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UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae

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Involvement of alpha-synuclein in Parkinson's disease and other neurodegenerative disorders

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The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

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The human ubiquitin-conjugating enzyme UbcH1 is involved in the repair of UV-damaged, alkylated and cross-linked DNA

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Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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Unscrambling the puzzle of biological machines: the importance of the details

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor

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The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

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p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

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CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

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Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

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A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

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7 January 2021

A family of ubiquitin-like proteins binds the ATPase domain of Hsp70-like Stch

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7 January 2021

Modulation of intracellular protein degradation by SSB1-SIS1 chaperon system in yeast S. cerevisiae.

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7 January 2021

Mapping the ubiquitin-binding domains in the p54 regulatory complex subunit of the Drosophila 26S protease.

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7 January 2021

Son1p is a component of the 26S proteasome of the yeast Saccharomyces cerevisiae

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7 January 2021

Proteasome function is dispensable under normal but not under heat shock conditions in Thermoplasma acidophilum

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The Arabidopsis homologue of an eIF3 complex subunit associates with the COP9 complex.

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Proteasome inhibition: A novel mechanism to combat asthma

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Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

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7 January 2021

Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

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7 January 2021

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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7 January 2021

RING finger proteins: mediators of ubiquitin ligase activity

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7 January 2021

Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

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7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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7 January 2021

The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.

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Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly

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Regulatory subunits of energy-dependent proteases

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7 January 2021

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7 January 2021

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

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SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

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7 January 2021

Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.

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7 January 2021

Geminin, an inhibitor of DNA replication, is degraded during mitosis

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7 January 2021

Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway.

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7 January 2021

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

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7 January 2021

The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation.

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An E3-like factor that promotes SUMO conjugation to the yeast septins

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Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

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7 January 2021

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

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7 January 2021

Ubiquitin, cellular inclusions and their role in neurodegeneration

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7 January 2021

Characterization of the ubiquitin-specific protease activity of the mouse/human Unp/Unph oncoprotein

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7 January 2021

The function of the proteasome system in MHC class I antigen processing.

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7 January 2021

Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development.

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7 January 2021

Angelman syndrome: a review of clinical and genetic aspects

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7 January 2021

Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin-B protein

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7 January 2021

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7 January 2021

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7 January 2021

Interferon regulatory factors: the next generation

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Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells.

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7 January 2021

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7 January 2021

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7 January 2021

The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development.

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7 January 2021

Cut and trim: generating MHC class I peptide ligands

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7 January 2021

Dis-assembly lines: the proteasome and related ATPase-assisted proteases

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7 January 2021

Structure and dynamics of molecular motors

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7 January 2021

The U box is a modified RING finger — a common domain in ubiquitination

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7 January 2021

Cut8, essential for anaphase, controls localization of 26S proteasome, facilitating destruction of cyclin and Cut2

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7 January 2021

The COP9 signalosome is essential for development of Drosophila melanogaster

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7 January 2021

The COP9/signalosome complex is conserved in fission yeast and has a role in S phase

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7 January 2021

Protein stability: the COP9 signalosome gets in on the act

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7 January 2021

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

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7 January 2021

The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex

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7 January 2021

A new large proteolytic complex distinct from the proteasome is present in the cytosol of fission yeast

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7 January 2021

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

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7 January 2021

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

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7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

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7 January 2021

Giant proteases: beyond the proteasome

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7 January 2021

Ubiquitin-dependent degradation of active Src.

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7 January 2021

Ubiquitin and its kin: how close are the family ties?

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7 January 2021

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

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7 January 2021

COP9 signalosome revisited: a novel mediator of protein degradation

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7 January 2021

The AAA team: related ATPases with diverse functions

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7 January 2021

Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

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7 January 2021

Proteasomes and other self-compartmentalizing proteases in prokaryotes

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7 January 2021

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

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7 January 2021

A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

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7 January 2021

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

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7 January 2021

Does this have a familiar RING?

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7 January 2021

A repetitive sequence in subunits of the 26S proteasome and 20S cyclosome (anaphase-promoting complex).

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7 January 2021

Self-compartmentalizing proteases.

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7 January 2021

The PCI domain: a common theme in three multiprotein complexes.

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7 January 2021

Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle

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7 January 2021

Retrograde protein translocation: ERADication of secretory proteins in health and disease

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7 January 2021

Regulatory subunit interactions of the 26S proteasome, a complex problem

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7 January 2021

Discrete proteolytic intermediates in the MHC class I antigen processing pathway and MHC I-dependent peptide trimming in the ER.

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7 January 2021

The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome

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https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A function for monoubiquitination in the internalization of a G protein-coupled receptor.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

PCI complexes: pretty complex interactions in diverse signaling pathways.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Assembly of the 26S proteasome is regulated by phosphorylation of the p45/Rpt6 ATPase subunit

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mechanism of ubiquitin conjugating enzyme E2-230K: catalysis involving a thiol relay?

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Formation of proteasome-PA700 complexes directly correlates with activation of peptidase activity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The 26S-proteasome: regulation and substrate recognition

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The base of the proteasome regulatory particle exhibits chaperone-like activity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A protein conjugation system essential for autophagy

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The ubiquitin pathway in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Targeted destabilization of HY5 during light-regulated development of Arabidopsis.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A regulatory link between ER-associated protein degradation and the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Evolution and function of ubiquitin-like protein-conjugation systems

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The MDM2 RING-finger domain is required to promote p53 nuclear export

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Structural basis for the activation of 20S proteasomes by 11S regulators

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Molecular chaperones and the art of recognizing a lost cause

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Themes and variations on ubiquitylation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Antigen processing by the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Protein regulation by monoubiquitin

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Rad23 links DNA repair to the ubiquitin/proteasome pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A role for the proteasome regulator PA28alpha in antigen presentation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cut2 proteolysis required for sister-chromatid seperation in fission yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A new group of conserved coactivators that increase the specificity of AP-1 transcription factors

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Structure of 20S proteasome from yeast at 2.4 A resolution

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Global unfolding of a substrate protein by the Hsp100 chaperone ClpA.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A gated channel into the proteasome core particle

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

UBA domains of DNA damage-inducible proteins interact with ubiquitin

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

UBE3A/E6-AP mutations cause Angelman syndrome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The ATP-dependent HslVU protease from Escherichia coli is a four-ring structure resembling the proteasome.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The generation of nfkb2 p52: mechanism and efficiency

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of the E7 human papillomavirus oncoprotein by the ubiquitin-proteasome system: targeting via ubiquitination of the N-terminal residue

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Subcellular localization of proteasomes and their regulatory complexes in mammalian cells.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Sequence elements that contribute to the degradation of yeast G alpha.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

AAA+ superfamily ATPases: common structure--diverse function

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inactivation of the 20S proteasome in Mycobacterium smegmatis.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of transcription factor IRF-1 by the ubiquitin-proteasome pathway. The C-terminal region governs the protein stability

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Physical association of ubiquitin ligases and the 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Skp2 is oncogenic and overexpressed in human cancers

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of proteasomal degradation by the gly-Ala repeat of Epstein-Barr virus is influenced by the length of the repeat and the strength of the degradation signal

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

ATP-dependent degradation of ubiquitin-protein conjugates

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Immunoelectron microscopic localization of the ubiquitin-activating enzyme E1 in HepG2 cells

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The mouse and human genes encoding the recognition component of the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Functional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Chaperone rings in protein folding and degradation.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of amino acid residues essential for von Willebrand factor binding to platelet glycoprotein Ib. Charged-to-alanine scanning mutagenesis of the A1 domain of human von Willebrand factor

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A proteolytic pathway that recognizes ubiquitin as a degradation signal

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Molecular cloning and expression of a 26 S protease subunit enriched in dileucine repeats

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Developmental changes of the 26 S proteasome in abdominal intersegmental muscles of Manduca sexta during programmed cell death.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A proteasome from the methanogenic archaeon Methanosarcina thermophila.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of ubiquitin-mediated proteolysis by the Arabidopsis 26 S protease subunit S5a.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Isolation, characterization, and partial purification of a novel ubiquitin-protein ligase, E3. Targeting of protein substrates via multiple and distinct recognition signals and conjugating enzymes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The ubiquitin-activating enzyme E1 is phosphorylated and localized to the nucleus in a cell cycle-dependent manner

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification, purification, and characterization of a PA700-dependent activator of the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Specific interactions between ATPase subunits of the 26 S protease

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Conservation and diversity of eukaryotic translation initiation factor eIF3

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Characterization of recombinant REGalpha, REGbeta, and REGgamma proteasome activators

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Specificity of the ubiquitin isopeptidase in the PA700 regulatory complex of 26 S proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Enzymes catalyzing ubiquitination and proteolytic processing of the p105 precursor of nuclear factor kappaB1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

NF-κB p105 Processing via the Ubiquitin-Proteasome Pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of three major sentrinization sites in PML

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

26 S Proteasome-mediated Production of an Authentic Major Histocompatibility Class I-restricted Epitope from an Intact Protein Substrate

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

E2/E3-mediated assembly of lysine 29-linked polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of alpha-synuclein by proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interferon regulatory factor 1 mediates the interferon-gamma induction of the human immunoproteasome subunit multicatalytic endopeptidase complex-like 1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

JAB1 interacts with both the progesterone receptor and SRC-1

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Activity and regulation of the centrosome-associated proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

p38JAB1 binds to the intracellular precursor of the lutropin/choriogonadotropin receptor and promotes its degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The human 26 S and 20 S proteasomes generate overlapping but different sets of peptide fragments from a model protein substrate.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

RGS4 is arginylated and degraded by the N-end rule pathway in vitro

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of the epstein-barr virus latent membrane protein 1 (LMP1) by the ubiquitin-proteasome pathway. Targeting via ubiquitination of the N-terminal residue

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Regulation of nuclear transport and degradation of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The nuclear ubiquitin-proteasome system degrades MyoD.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A HECT domain E3 enzyme assembles novel polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

U box proteins as a new family of ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Deubiquitinating enzymes: a new class of biological regulators

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitination of the yeast a-factor receptor

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Aggresomes: a cellular response to misfolded proteins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Dynamic association of proteasomal machinery with the centrosome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The APC11 RING-H2 finger mediates E2-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Yeast cycloheximide-resistant crl mutants are proteasome mutants defective in protein degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Protein folding and misfolding inside and outside the cell

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Localization of the 26S proteasome during mitosis and meiosis in fission yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A novel protein modification pathway related to the ubiquitin system

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubc8p functions in catabolite degradation of fructose-1, 6-bisphosphatase in yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Recognition of the polyubiquitin proteolytic signal

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Monoubiquitin carries a novel internalization signal that is appended to activated receptors

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

JAB1/CSN5 and the COP9 signalosome. A complex situation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin-associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi-ubiquitin chain assembly

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of Id proteins by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

TAP prefers to transport melanoma antigenic peptides which are longer than the optimal T-cell epitope: evidence for further processing in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Regulation of the epithelial sodium channel (ENaC) by accessory proteins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Polyglutamine pathogenesis.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Protein quality control: triage by chaperones and proteases

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The 19S complex of the proteasome regulates nucleotide excision repair in yeast.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Arabidopsis cop8 and fus4 mutations define the same gene that encodes subunit 4 of the COP9 signalosome.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Multiubiquitin chain binding subunit MCB1 (RPN10) of the 26S proteasome is essential for developmental progression in Physcomitrella patens.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of ubiquitin ligases required for skeletal muscle atrophy

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of BIME as a subunit of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Role of Cue1p in ubiquitination and degradation at the ER surface

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Budding yeast Cdc20: a target of the spindle checkpoint.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Identification of a cullin homology region in a subunit of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A giant protease with potential to substitute for some functions of the proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

One ring to rule a superfamily of E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Detecting and measuring cotranslational protein degradation in vivo

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

In vivo half-life of a protein is a function of its amino-terminal residue

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of G alpha by the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Biochemical and physical properties of the Methanococcus jannaschii 20S proteasome and PAN, a homolog of the ATPase (Rpt) subunits of the eucaryal 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The Glc7 type 1 protein phosphatase of Saccharomyces cerevisiae is required for cell cycle progression in G2/M.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The regulatory particle of the Saccharomyces cerevisiae proteasome.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Rpn9 is required for efficient assembly of the yeast 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Regulatory networks revealed by transcriptional profiling of damaged Saccharomyces cerevisiae cells: Rpn4 links base excision repair with proteasomes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

1 reference

7 January 2021

The 26S proteasome: a molecular machine designed for controlled proteolysis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The anaphase-promoting complex: new subunits and regulators

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

1 reference

7 January 2021

Chaperonin-mediated protein folding

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Vacuolar import of proteins and organelles from the cytoplasm

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

SUMO--nonclassical ubiquitin

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Degradation of cell proteins and the generation of MHC class I-presented peptides

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Two-hybrid analysis of the Saccharomyces cerevisiae 26S proteasome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Biosynthesis and degradation of CFTR.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021

Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2001

7 January 2021