The lamellipodium: where motility begins (Q28202993)

Europe PubMed Central

title

The lamellipodium: where motility begins (English)

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author

Klemens Rottner

4

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Theresia Stradal

object named as

Theresia Stradal

2

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Emmanuel Vignal

3

object named as

Emmanuel Vignal

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author name string

J Victor Small

Subcellular distribution of rhodamine-actin microinjected into living fibroblastic cells

1

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language of work or name

English

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publication date

March 2002

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published in

Trends in Cell Biology

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volume

12

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issue

3

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page(s)

112-20

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cites work

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The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly

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Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

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VASP dynamics during lamellipodia protrusion

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Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

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A WASp-VASP complex regulates actin polymerization at the plasma membrane.

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Negative regulation of fibroblast motility by Ena/VASP proteins

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WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

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Scar/WAVE is localised at the tips of protruding lamellipodia in living cells

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Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold

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7 January 2021

The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia

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7 January 2021

Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes

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Regulating cellular actin assembly

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Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling

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7 January 2021

Rho GTPases and the actin cytoskeleton

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7 January 2021

Rho family proteins: coordinating cell responses

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

Activation of Rac and Cdc42 by integrins mediates cell spreading

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Rho GTPases and signaling networks

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Signaling from Ras to Rac and beyond: not just a matter of GEFs

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Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

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7 January 2021

Localized Rac activation dynamics visualized in living cells

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7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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7 January 2021

Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

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7 January 2021

GEF at work: Vav in protruding filopodia

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7 January 2021

Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells

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7 January 2021

N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

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7 January 2021

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

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7 January 2021

Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin

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7 January 2021

Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

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7 January 2021

p21-activated protein kinase: a crucial component of morphological signaling?

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7 January 2021

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The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins

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7 January 2021

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

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7 January 2021

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

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7 January 2021

Actin machinery: pushing the envelope.

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7 January 2021

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

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7 January 2021

New tricks for an old dog?

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7 January 2021

Activation of the Arp2/3 complex by the actin filament binding protein Abp1p

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7 January 2021

Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation

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7 January 2021

Drebrin particles: components in the ensemble of proteins regulating actin dynamics of lamellipodia and filopodia.

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Actin-binding protein requirement for cortical stability and efficient locomotion

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7 January 2021

Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells

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Filamins as integrators of cell mechanics and signalling

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7 January 2021

Structural and functional aspects of filamins

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7 January 2021

The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin

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7 January 2021

Ultrastructural localization of alpha-actinin and filamin in cultured cells with the immunogold staining (IGS) method

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7 January 2021

The coronin family of actin-associated proteins

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7 January 2021

Architectural dynamics and gene replacement of coronin suggest its role in cytokinesis

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7 January 2021

Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction

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7 January 2021

Parallel actin bundles and their multiple actin-bundling proteins.

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7 January 2021

Phosphorylation of human fascin inhibits its actin binding and bundling activities

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7 January 2021

Cell-matrix adhesions differentially regulate fascin phosphorylation

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7 January 2021

Regulation of actin filament cross-linking and bundle shape in Drosophila bristles

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7 January 2021

Inhibition by drebrin of the actin-bundling activity of brain fascin, a protein localized in filopodia of growth cones

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7 January 2021

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures

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7 January 2021

Lamellipodia architecture: actin filament turnover and the lateral flow of actin filaments during motility

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7 January 2021

Mechanism of lateral movement of filopodia and radial actin bundles across neuronal growth cones

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7 January 2021

Regulated tyrosine phosphorylation at the tips of growth cone filopodia

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7 January 2021

Putting a new twist on actin: ADF/cofilins modulate actin dynamics

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7 January 2021

Hyperosmotic stress-induced reorganization of actin bundles in Dictyostelium cells over-expressing cofilin

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7 January 2021

Actin filament organization in the fish keratocyte lamellipodium.

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7 January 2021

Visualization and molecular analysis of actin assembly in living cells

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7 January 2021

Comparisons of CapG and gelsolin-null macrophages: demonstration of a unique role for CapG in receptor-mediated ruffling, phagocytosis, and vesicle rocketing

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7 January 2021

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

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7 January 2021

The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation

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7 January 2021

A role for myosin VII in dynamic cell adhesion

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7 January 2021

The Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of actin polarization

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7 January 2021

A role for myosin-I in actin assembly through interactions with Vrp1p, Bee1p, and the Arp2/3 complex

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7 January 2021

An intact SH3 domain is required for myosin I-induced actin polymerization.

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7 January 2021

The Dictyostelium CARMIL protein links capping protein and the Arp2/3 complex to type I myosins through their SH3 domains

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7 January 2021

Myosin-V: head to tail.

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7 January 2021

Function of myosin-V in filopodial extension of neuronal growth cones

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7 January 2021

Myosin VI is an actin-based motor that moves backwards

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7 January 2021

Myosin drives retrograde F-actin flow in neuronal growth cones

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7 January 2021

Getting to the point with myosin VI.

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7 January 2021

Accumulation of talin in nodes at the edge of the lamellipodium and separate incorporation into adhesion plaques at focal contacts in fibroblasts

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7 January 2021

The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

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7 January 2021

Secrets of actin-based motility revealed by a bacterial pathogen

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7 January 2021

Cell motility driven by actin polymerization

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7 January 2021

Visualising the actin cytoskeleton

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7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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7 January 2021

Intact alpha-actinin molecules are needed for both the assembly of actin into the tails and the locomotion of Listeria monocytogenes inside infected cells

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7 January 2021

Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles

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7 January 2021

10.1016/S0962-8924(01)02237-1

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

149150

149150

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference