A mouse model for medulloblastoma and basal cell nevus syndrome (Q28206586)

12 December 2020

Altered neural cell fates and medulloblastoma in mouse patched mutants

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12 December 2020

The Hedgehog and Wnt signalling pathways in cancer

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12 December 2020

Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study.

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12 December 2020

Gli genes in development and cancer

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12 December 2020

Variable imprinting of H19 and IGF2 in fetal cerebellum and medulloblastoma.

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12 December 2020

Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours

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12 December 2020

Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo.

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12 December 2020

Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.

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12 December 2020

Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice

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12 December 2020

Exploiting the lacZ reporter gene for quantitative analysis of disseminated tumor growth within the brain: use of the lacZ gene product as a tumor antigen, for evaluation of antigenic modulation, and to facilitate image analysis of tumor growth in s

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12 December 2020

In situ detection of transcriptionally active chromatin and genetic regulatory elements in individual viable mammalian cells.

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12 December 2020

Concordant loss of imprinting of the human insulin-like growth factor II gene promoters in cancer

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12 December 2020

Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

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12 December 2020

Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched

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12 December 2020

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.

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12 December 2020

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

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12 December 2020

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

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12 December 2020

Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors.

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12 December 2020

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

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12 December 2020

Identification of PATCHED mutations in medulloblastomas by direct sequencing

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12 December 2020

Nevoid basal-cell carcinoma syndrome

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12 December 2020

The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8

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12 December 2020

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

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12 December 2020

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

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12 December 2020

Gene expression and cell fusion analyzed by lacZ complementation in mammalian cells

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12 December 2020

The gene for the naevoid basal cell carcinoma syndrome acts as a tumour-suppressor gene in medulloblastoma

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12 December 2020

Sporadic medulloblastomas contain PTCH mutations.

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12 December 2020

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

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12 December 2020

Activating Smoothened mutations in sporadic basal-cell carcinoma

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12 December 2020

Rhabdomyosarcoma: an overview

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12 December 2020

Case report: nasopharyngeal rhabdomyosarcoma and Gorlin's naevoid basal cell carcinoma syndrome

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12 December 2020

An absolute requirement for Cubitus interruptus in Hedgehog signaling.

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12 December 2020

Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors

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12 December 2020

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

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12 December 2020

Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome

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12 December 2020

Nonmelanoma skin cancer in the United States: incidence.

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12 December 2020

A frequent activated smoothened mutation in sporadic basal cell carcinomas

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12 December 2020

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

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12 December 2020

Childhood medulloblastoma: progress and future challenges

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12 December 2020

Hedgehog and patched in neural development and disease

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12 December 2020

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12 December 2020

Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.

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12 December 2020

Basal cell carcinomas in mice overexpressing sonic hedgehog

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12 December 2020

Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.

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12 December 2020

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

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12 December 2020

Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors

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12 December 2020

Identification of an amplified, highly expressed gene in a human glioma

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12 December 2020

Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study

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12 December 2020

Cytogenetic and molecular genetic abnormalities in primitive neuroectodermal tumors of the central nervous system.

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12 December 2020

The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched

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12 December 2020

Quality of long-term survival in young children with medulloblastoma

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12 December 2020

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

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12 December 2020