Hodgkin's lymphoma and CD30 signal transduction (Q28207526)

International Journal of Hematology

Europe PubMed Central

title

Hodgkin's lymphoma and CD30 signal transduction (English)

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author name string

Ryouichi Horie

series ordinal

1

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Masaaki Higashihara

series ordinal

2

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Toshiki Watanabe

series ordinal

3

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language of work or name

English

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publication date

January 2003

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published in

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volume

77

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issue

1

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page(s)

37-47

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cites work

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Association of a RING finger protein with the cytoplasmic domain of the human type-2 tumour necrosis factor receptor

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Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cells

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Involvement of Sp1 and microsatellite repressor sequences in the transcriptional control of the human CD30 gene

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Regulation of CD30 antigen expression and its potential significance for human disease

21 January 2018

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Structure of the Hodgkin's lymphoma-associated human CD30 gene and the influence of a microsatellite region on its expression in CD30(+) cell lines.

21 January 2018

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12 December 2020

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

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12 December 2020

Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.

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12 December 2020

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

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12 December 2020

Cross-linking of CD30 induces HIV expression in chronically infected T cells

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12 December 2020

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

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12 December 2020

CD30/TNF receptor-associated factor interaction: NF-kappa B activation and binding specificity

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12 December 2020

A novel RING finger protein interacts with the cytoplasmic domain of CD40

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12 December 2020

Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines.

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12 December 2020

Preferential expression of CD30 by human CD4+ T cells producing Th2-type cytokines

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12 December 2020

Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells

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12 December 2020

Acute infectious mononucleosis. CD30 (Ki-1) antigen expression and histologic correlations

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12 December 2020

High serum level of soluble CD30 in acute primary HIV-1 infection

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12 December 2020

Expression of the tumor necrosis factor receptor-associated factors (TRAFs) 1 and 2 is a characteristic feature of Hodgkin and Reed-Sternberg cells

1 reference

12 December 2020

Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views

1 reference

12 December 2020

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

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12 December 2020

Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB.

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12 December 2020

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

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12 December 2020

Aberrant rel/nfkb genes and activity in human cancer

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12 December 2020

CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

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12 December 2020

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

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12 December 2020

Increased serum levels of soluble IL-2 receptor, CD30 and CD8 molecules, and gamma-interferon in angioimmunoblastic lymphadenopathy: possible pathogenetic role of immunoactivation mechanisms

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12 December 2020

Variable expression of Epstein-Barr virus latent membrane protein I in Reed-Sternberg cells of Hodgkin's disease

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12 December 2020

T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors

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12 December 2020

A Hodgkin cell-specific antigen is expressed on a subset of auto- and alloactivated T (helper) lymphoblasts

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12 December 2020

Structure and expression of murine CD30 and its role in cytokine production

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12 December 2020

CD30 expression does not discriminate between human Th1- and Th2-type T cells

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12 December 2020

CD30 (Ki-1) expression in adult T-cell leukaemia/lymphoma is associated with distinctive immunohistological and clinical characteristics

1 reference

12 December 2020

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease

1 reference

12 December 2020

Activation of Hodgkin cells via the CD30 receptor induces autocrine secretion of interleukin-6 engaging the NF-kappabeta transcription factor.

1 reference

12 December 2020

Activation of HIV expression by CD30 triggering in CD4+ T cells from HIV-infected individuals

1 reference

12 December 2020

Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

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12 December 2020

A novel domain in the CD30 cytoplasmic tail mediates NFkappaB activation

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12 December 2020

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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12 December 2020

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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12 December 2020

Translocation of TRAF proteins regulates apoptotic threshold of cells

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12 December 2020

THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

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12 December 2020

CD30 expression by CD8+ T cells producing type 2 helper cytokines. Evidence for large numbers of CD8+CD30+ T cell clones in human immunodeficiency virus infection

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12 December 2020

CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells

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12 December 2020

Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB.

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12 December 2020

Clinical implications of serum levels of soluble CD30 in 70 adult anaplastic large-cell lymphoma patients

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12 December 2020

The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB

1 reference

12 December 2020

The Epstein-Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation

1 reference

12 December 2020

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

1 reference

12 December 2020

Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma

1 reference

12 December 2020

TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor

1 reference

12 December 2020

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

1 reference

12 December 2020

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

12 December 2020

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1 reference

12 December 2020

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

1 reference

12 December 2020

Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells

1 reference

12 December 2020

High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells

1 reference

12 December 2020

CD30: expression and function in health and disease

1 reference

12 December 2020

CD30 ligand expression in nonmalignant and Hodgkin's disease-involved lymphoid tissues

1 reference

12 December 2020

Reed-Sternberg cell genome expression supports a B-cell lineage.

1 reference

12 December 2020

The nature of Reed-Sternberg cells: phenotype, genotype, and other properties.

1 reference

12 December 2020

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

1 reference

12 December 2020

Analysis of the human and mouse promoter region of the non-Hodgkin's lymphoma-associated CD30 gene.

1 reference

12 December 2020

Rel/NF-kappa B/I kappa B story

1 reference

12 December 2020

Detection of a soluble form of the CD30 antigen in sera of patients with lymphoma, adult T-cell leukemia and infectious mononucleosis

1 reference

12 December 2020

Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation

1 reference

12 December 2020

TRAF6 is a signal transducer for interleukin-1

1 reference

12 December 2020

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

1 reference

12 December 2020

CD30 and type 2 T helper (Th2) responses.

1 reference

12 December 2020

CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals

1 reference

12 December 2020

Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor

1 reference

12 December 2020

Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells

1 reference

12 December 2020

Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas.

1 reference

12 December 2020

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1 reference

12 December 2020

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

12 December 2020

Serum level of the soluble form of the CD30 molecule identifies patients with Hodgkin's disease at high risk of unfavorable outcome.

1 reference

12 December 2020

Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells.

1 reference

12 December 2020

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

12 December 2020

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

12 December 2020

Regulation of murine B cell growth and differentiation by CD30 ligand

1 reference

12 December 2020

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

1 reference

12 December 2020

Pathophysiology of Hodgkin's disease: functional and molecular aspects

1 reference

12 December 2020

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1 reference

12 December 2020

CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.

1 reference

12 December 2020

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

1 reference

12 December 2020

CD30, Th2 cytokines and HIV infection: a complex and fascinating link

1 reference

12 December 2020

Constitutive activation of NF-kB in human thymocytes

1 reference

12 December 2020

Identification of Hodgkin and Sternberg-reed cells as a unique cell type derived from a newly-detected small-cell population

1 reference

12 December 2020

Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma

1 reference

12 December 2020

CD30 ligand is expressed on resting normal and malignant human B lymphocytes

1 reference

12 December 2020

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

1 reference

12 December 2020

Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

1 reference

12 December 2020

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

1 reference

12 December 2020

A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines

1 reference

12 December 2020

CD30 defines a subset of activated human T cells that produce IFN-gamma and IL-5 and exhibit enhanced B cell helper activity

1 reference

12 December 2020

A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40

1 reference

12 December 2020

The diagnostic significance of the CD30 (Ki-1) antigen

1 reference

12 December 2020

CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins

1 reference

12 December 2020

Transducers of life and death: TNF receptor superfamily and associated proteins

1 reference

12 December 2020

Cellular origin and clonality of classic Hodgkin's lymphoma: immunophenotypic and molecular studies

1 reference

12 December 2020

The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death

1 reference

12 December 2020

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

1 reference

12 December 2020

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

1 reference

12 December 2020

Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily

1 reference

12 December 2020

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

1 reference

12 December 2020

The restricted expression pattern of the Hodgkin's lymphoma-associated cytokine receptor CD30 is regulated by a minimal promoter

1 reference

12 December 2020

High CD30 ligand expression by epithelial cells and Hassal's corpuscles in the medulla of human thymus

1 reference

12 December 2020

Tumor necrosis factor receptor-associated factor 1 is overexpressed in Reed-Sternberg cells of Hodgkin's disease and Epstein-Barr virus-transformed lymphoid cells

1 reference

12 December 2020

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells

1 reference

12 December 2020

Clinicopathological features of adult T-cell leukemia with CD30 antigen expression

1 reference

12 December 2020

Photo-oxidative stress down-modulates the activity of nuclear factor-kappaB via involvement of caspase-1, leading to apoptosis of photoreceptor cells

1 reference

12 December 2020

Ki-1 (CD30) antigen is released by Ki-1-positive tumor cells in vitro and in vivo. I. Partial characterization of soluble Ki-1 antigen and detection of the antigen in cell culture supernatants and in serum by an enzyme-linked immunosorbent assay

1 reference

12 December 2020

Catalysis by a multiprotein IkappaB kinase complex

1 reference

12 December 2020

Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line

1 reference

12 December 2020

BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol-resistant epitope

1 reference

12 December 2020

CD30 ligand is frequently expressed in human hematopoietic malignancies of myeloid and lymphoid origin

1 reference

12 December 2020