Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis (Q35606094)

9 August 2017

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis (English)

1 reference

9 August 2017

0 references

1 reference

B Kaltschmidt

1

1 reference

9 August 2017

M Uherek

2

1 reference

9 August 2017

H Wellmann

3

1 reference

9 August 2017

B Volk

4

1 reference

9 August 2017

C Kaltschmidt

5

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 August 1999

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

1 reference

9 August 2017

96

1 reference

9 August 2017

9409-9414

1 reference

9 August 2017

16

1 reference

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

9 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Progressive neuronal injury associated with amyloid plaque formation in Alzheimer disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

High constitutive NF-kappaB activity mediates resistance to oxidative stress in neuronal cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Receptors for advanced glycosylation endproducts in human brain: role in brain homeostasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Nuclear translocation of NF-kappaB in cholinergic neurons of patients with Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

NF-kappaB activation: the I kappaB kinase revealed?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Neuropathological diagnosis of Alzheimer's disease: a perspective from longitudinal clinicopathological studies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Frequency of stages of Alzheimer-related lesions in different age categories

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

I kappa B proteins: structure, function and regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Identification and characterization of an IkappaB kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

NF-kappa B: a crucial transcription factor for glial and neuronal cell function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Presenilins: genes for life and death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

The pathogenesis of senile plaques

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Enhancement of immunoreactivity for NF-kappa B in human cerebral infarctions.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Normal and abnormal biology of the beta-amyloid precursor protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Constitutive NF-kappa B activity in neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Hydrogen peroxide mediates amyloid beta protein toxicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Regulation of NF-kappa B activity in rat dorsal root ganglia and PC12 cells by tumour necrosis factor and nerve growth factor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Selective recognition of the activated form of transcription factor NF-kappa B by a monoclonal antibody

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Gene therapy. Intracellular immunization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Amyloid plaque core protein in Alzheimer disease and Down syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Ultrastructural studies of the cells forming amyloid fibers in classical plaques.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Detection of HLA-DR on microglia in the human brain is a function of both clinical and technical factors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

IKAP is a scaffold protein of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Alteration of transcription factors NF-kappaB and STAT1 in Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

The effects of 5-HT3 receptor antagonists on cognitive performance in aged monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Inhibition of TNF-induced apoptosis by NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Microglia in cerebellar plaques in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17796

Alteration of Transcription Factor Binding Activities in the Ischemic Rat-Brain

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9409

Optimized protocol for biolistic transfection of brain slices and dissociated cultured neurons with a hand-held gene gun

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10430956

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Traumatic spinal cord injury induces nuclear factor-kappaB activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10430956

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.16.9409

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference