HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation (Q28211642)

2

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J J Lum

3

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A Alam

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D H Lynch

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B Beckett

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P H Krammer

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R P Sekaly

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A D Badley

Cell Death & Differentiation

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language of work or name

English

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publication date

November 2002

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published in

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volume

9

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issue

11

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page(s)

1172-84

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cites work

Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Priming of human CD4+ antigen-specific T cells to undergo apoptosis by HIV-infected monocytes. A two-step mechanism involving the gp120 molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Exposure of resting peripheral blood T cells to HIV-1 particles generates CD25+ killer cells in a small subset, leading to induction of apoptosis in bystander cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

CD4+ blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

HIV-1 upregulates Fas ligand expression in CD4+ T cells in vitro and in vivo: association with Fas-mediated apoptosis and modulation by aurintricarboxylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Fas ligand mediates activation-induced cell death in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Interleukin-1 beta converting enzyme-like protease involvement in Fas-induced and activation-induced peripheral blood T cell apoptosis in HIV infection. TNF-related apoptosis-inducing ligand can mediate activation-induced T cell death in HIV infecti

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

TRAIL/Apo-2-ligand-induced apoptosis in human T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

HIV-induced apoptosis of activated primary CD4+ T lymphocytes is not mediated by Fas-Fas ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Human immunodeficiency virus type 1 Nef protein on the cell surface is cytocidal for human CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

In vitro cytocidal effects of human immunodeficiency virus type 1 Nef on unprimed human CD4+ T cells without MHC restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

DNA fragmentation induced by protease activation in p53-null human leukemia HL60 cells undergoing apoptosis following treatment with the topoisomerase I inhibitor camptothecin: cell-free system studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Mitochondrial control of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Apoptosis regulators from DNA viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Human immunodeficiency virus type 1 protease cleaves the intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

21 January 2018

HIV-protease inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Biochemical characteristics of caspases-3, -6, -7, and -8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Caspase-independent cell killing by Fas-associated protein with death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Reaper-induced apoptosis in a vertebrate system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Catalytic properties of the caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobic*hydrophobic- or -aromatic*pro- cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

FLICE Induced Apoptosis in a Cell-free System

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

Cytotoxic monocytes in the blood of HIV type 1-infected subjects destroy targeted T cells in a CD95-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

Activation-induced peripheral blood T cell apoptosis is Fas independent in HIV-infected individuals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

HIV-1 Tat protein and its inhibitor Ro 24-7429 inhibit lymphocyte proliferation and induce apoptosis in peripheral blood mononuclear cells from healthy donors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

Bcl-2 regulates activation of apoptotic proteases in a cell-free system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

CD95(APO-1/Fas)-mediated apoptosis: live and let die

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

Studies on the specificity of HIV protease: an application of Markov chain theory

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

A cellular anti-apoptosis protein is cleaved by the HIV-1 protease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021

An assay for DNA fragmentation in apoptosis without phenol/chloroform extraction and ethanol precipitation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401094

7 January 2021