The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3 (Q28213852)

2

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S A Schreiner

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M Birke

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T H Winkler

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R K Slany

Basic local alignment search tool

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language of work or name

English

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publication date

25 January 2001

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published in

Oncogene

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volume

20

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issue

4

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page(s)

411-9

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cites work

1 reference

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HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties

21 January 2018

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Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells

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Chromatin remodeling machines: similar motors, ulterior motives

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Myc-mediated transformation: the repression connection

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An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 January 2018

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Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein

21 January 2018

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Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

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A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

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The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

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The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

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ENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+.

21 January 2018

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The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

21 January 2018

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Identification and analysis of a third mouse Polycomb gene, MPc3

21 January 2018

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

21 January 2018

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Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

21 January 2018

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Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines

21 January 2018

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Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

21 January 2018

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Oncogenic transcription factors in the human acute leukemias

21 January 2018

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Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis

21 January 2018

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The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

21 January 2018

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Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

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Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key?

21 January 2018

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Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

21 January 2018

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The trithorax-group and polycomb-group chromatin modifiers: implications for disease

21 January 2018

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ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204108

Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein

21 January 2018

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MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204108

Altered Hox expression and segmental identity in Mll-mutant mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204108

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204108

The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204108