Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B) (Q28216177)

2

0 references

Min Liang

3

0 references

Weiguo Zhai

4

0 references

Xia Lin

A combination treatment of c-myc antisense DNA with all-trans-retinoic acid inhibits cell proliferation by downregulating c-myc expression in small cell lung cancer

5

0 references

language of work or name

English

0 references

publication date

January 2002

0 references

published in

Molecular Cell

0 references

volume

9

0 references

page(s)

133-43

0 references

issue

1

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Role of transforming growth factor beta in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Myc-mediated transformation: the repression connection

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Inhibition of c-myc expression in cells by targeting an RNA-protein interaction using antisense oligonucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

c-Myc target genes involved in cell growth, apoptosis, and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Smads: transcriptional activators of TGF-beta responses

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Histone deacetylase 1 can repress transcription by binding to Sp1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Transforming growth factor-beta (TGF-beta)-induced down-regulation of cyclin A expression requires a functional TGF-beta receptor complex. Characterization of chimeric and truncated type I and type II receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Molecular mechanisms of inactivation of TGF-beta receptors during carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Transcriptional control by the TGF-beta/Smad signaling system

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

MYC oncogenes and human neoplastic disease

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Specificity, diversity, and regulation in TGF-beta superfamily signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

New Myc-interacting proteins: a second Myc network emerges

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Repression of p15INK4b expression by Myc through association with Miz-1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Antitumor effects of antisense phosphorothioate c-myc oligodeoxynucleotides: a question of mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

p53-independent role of MDM2 in TGF-beta1 resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

1 reference

7 January 2021

Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900430-0

7 January 2021