The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation (Q33667278)

28 July 2017

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title

The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation (English)

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28 July 2017

Cole MD

1

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28 July 2017

McMahon SB

series ordinal

2

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28 July 2017

language of work or name

English

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publication date

1 May 1999

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28 July 2017

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28 July 2017

18

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28 July 2017

19

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28 July 2017

2916-2924

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202748

28 July 2017

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cites work

Sequence-specific transcriptional activation by Myc and repression by Max.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The ornithine decarboxylase gene is a transcriptional target of c-Myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

L-myc cooperates with ras to transform primary rat embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Binding of myc proteins to canonical and noncanonical DNA sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Myc and Max associate in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Myc versus USF: discrimination at the cad gene is determined by core promoter elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

An essential domain of the c-myc protein interacts with a nuclear factor that is also required for E1A-mediated transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The myc oncogene: its role in transformation and differentiation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Myc-mediated transformation: the repression connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The transactivation potential of a c-Myc N-terminal region (residues 92-143) is regulated by growth factor/Ras signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-Myc target genes involved in cell growth, apoptosis, and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The MYC protein activates transcription of the alpha-prothymosin gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The role of c-myc in cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

1 reference

7 January 2021

Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Determination of the c-MYC DNA-binding site

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Histone deacetylase activity is required for full transcriptional repression by mSin3A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

An amino-terminal c-myc domain required for neoplastic transformation activates transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Myc and Max proteins possess distinct transcriptional activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

A new class of yeast transcriptional activators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Dominant negative mutants of Myc inhibit cooperation of both Myc and adenovirus serotype-5 E1a with Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Intracellular association of the protein product of the c-myc oncogene with the TATA-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

myc function and regulation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Histone-like TAFs within the PCAF histone acetylase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

B-myc inhibits neoplastic transformation and transcriptional activation by c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

ESA1 is a histone acetyltransferase that is essential for growth in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Identification of downstream-initiated c-Myc proteins which are dominant-negative inhibitors of transactivation by full-length c-Myc proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Definition of regions in human c-myc that are involved in transformation and nuclear localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Cloning of mid-G1 serum response genes and identification of a subset regulated by conditional myc expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

c-myc activates RCC1 gene expression through E-box elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

The interferon-inducible murine p48 (ISGF3gamma) gene is regulated by protooncogene c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

N-myc can cooperate with ras to transform normal cells in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Transcriptional control of the endogenous MYC protooncogene by antisense RNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Cell cycle regulation of E2F site occupation in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202748

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202748

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Dimensions Publication ID

28 July 2017

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1 reference