The proto-oncogene BCL-6 in normal and malignant B cell development (Q28216775)

Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching

Europe PubMed Central

title

The proto-oncogene BCL-6 in normal and malignant B cell development (English)

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author name string

Huifeng Niu

series ordinal

1

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language of work or name

English

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publication date

December 2002

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published in

Hematological Oncology

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volume

20

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issue

4

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page(s)

155-66

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cites work

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Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription

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Significance of rearrangement of the BCL6 gene in B-cell lymphoid neoplasms

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Molecular pathogenesis of B cell malignancy: the role of BCL-6

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Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

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PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma

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Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes

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Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas

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Cloning of a breakpoint cluster region at band 3q27 involved in human non-Hodgkin's lymphoma

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LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

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7 January 2021

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

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7 January 2021

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

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7 January 2021

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

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7 January 2021

Disruption of the Bcl6 gene results in an impaired germinal center formation

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7 January 2021

Characterization of the promoter region of human BCL-6 gene

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7 January 2021

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

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7 January 2021

Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein

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7 January 2021

The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.

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7 January 2021

Recognition DNA sequence of a novel putative transcription factor, BCL6.

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7 January 2021

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

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7 January 2021

BCL-6 is phosphorylated at multiple sites in its serine- and proline-clustered region by mitogen-activated protein kinase (MAPK) in vivo

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7 January 2021

Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor

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7 January 2021

Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers

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7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

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7 January 2021

Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6.

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7 January 2021

The central role of the CD40-ligand and CD40 pathway in T-lymphocyte-mediated differentiation of B lymphocytes

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7 January 2021

T-cell subsets (Th1 versus Th2).

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7 January 2021

The biology of Stat4 and Stat6

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7 January 2021

Signaling and transcription in T helper development

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7 January 2021

T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6.

1 reference

7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

1 reference

7 January 2021

Transcription factors of the NFAT family: regulation and function

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7 January 2021

Transcription factors in lymphocyte development--T and B cells get together

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7 January 2021

ROG, repressor of GATA, regulates the expression of cytokine genes

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7 January 2021

BCL-6 regulates chemokine gene transcription in macrophages

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7 January 2021

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

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7 January 2021

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

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7 January 2021

Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 ligand/CD40

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7 January 2021

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

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7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

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7 January 2021

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.

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7 January 2021

Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

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7 January 2021

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

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7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

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7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

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7 January 2021

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7 January 2021

The proto-oncogene Bc16 inhibits apoptotic cell death in differentiation-induced mouse myogenic cells

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7 January 2021

Adenovirus-mediated high expression of BCL-6 in CV-1 cells induces apoptotic cell death accompanied by down-regulation of BCL-2 and BCL-X(L).

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7 January 2021

A matter of life and cell death

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7 January 2021

Rearrangements of bcl-6, bcl-2, c-myc and 6q deletion in B-diffuse large-cell lymphoma: Clinical relevance in 71 patients

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7 January 2021

Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma

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7 January 2021