Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE (Q28217217)

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object named as

K Joseph Hurt

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Solomon Halbert Snyder

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object named as

Solomon H Snyder

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author name string

Keqiang Ye

1

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Bahman Aghdasi

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Hongbo R Luo

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John L Moriarity

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Frederick Y Wu

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Jenny J Hong

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Sun Sik Bae

Overexpression of phosphoinositide-specific phospholipase Cgamma in NIH 3T3 cells promotes transformation and tumorigenicity

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language of work or name

English

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publication date

31 January 2002

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published in

Nature

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volume

415

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issue

6871

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page(s)

541-4

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cites work

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Phospholipase C-gamma 1 can induce DNA synthesis by a mechanism independent of its lipase activity

21 January 2018

1 reference

An SH3 domain is required for the mitogenic activity of microinjected phospholipase C-gamma 1.

21 January 2018

1 reference

Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

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1 reference

Structural basis for the binding of proline-rich peptides to SH3 domains

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1 reference

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

21 January 2018

1 reference

The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo

21 January 2018

1 reference

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

21 January 2018

1 reference

Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha.

21 January 2018

1 reference

Identification of PI-PLC beta 1, gamma 1, and delta 1 in rat liver: subcellular distribution and relationship to inositol lipid nuclear signalling.

21 January 2018

1 reference

Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic differentiation of HL-60 cells

21 January 2018

1 reference

Phospholipase C-gamma as a signal-transducing element

21 January 2018

1 reference

PLC gamma 1 Src homology domain induces mitogenesis in quiescent NIH 3T3 fibroblasts

21 January 2018

1 reference

GEFs: structural basis for their activation of small GTP-binding proteins

21 January 2018

1 reference

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

21 January 2018

1 reference

Direct interaction of SOS1 Ras exchange protein with the SH3 domain of phospholipase C-gamma1

21 January 2018

1 reference

A new function for phospholipase C-gamma1: coupling to the adaptor protein GRB2

21 January 2018

1 reference

Engagement of the T lymphocyte antigen receptor regulates association of son-of-sevenless homologues with the SH3 domain of phospholipase Cgamma1

21 January 2018

1 reference

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

21 January 2018

1 reference

Activation of phosphatidylinositol 3-kinase by insulin

21 January 2018

1 reference

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

21 January 2018

1 reference

The GTPase dynamin binds to and is activated by a subset of SH3 domains

21 January 2018

1 reference

Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor

21 January 2018

1 reference