The skin barrier as an innate immune element (Q28235928)

Seminars in Immunopathology

Europe PubMed Central

title

The skin barrier as an innate immune element (English)

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author name string

Peter M Elias

series ordinal

1

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language of work or name

English

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publication date

April 2007

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published in

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volume

29

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issue

1

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page(s)

3-14

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exact match

https://scigraph.springernature.com/pub.10.1007/s00281-007-0060-9

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cites work

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Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity

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Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity

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Palmitoleic acid isomer (C16:1delta6) in human skin sebum is effective against gram-positive bacteria

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Interactions among stratum corneum defensive functions

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Secreted proteases from pathogenic fungi

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Formation of active IL-1 beta from pro-IL-1 beta catalyzed by stratum corneum chymotryptic enzyme in vitro

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Ordered structure of the epidermis

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Stratum corneum acidification is impaired in moderately aged human and murine skin

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Fatty acids are required for epidermal permeability barrier function

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pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion

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A proteolytic cascade of kallikreins in the stratum corneum

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Identification of Late Differentiation Antigens of Human Cornified Epithelia, Expressed in Re-Organized Desmosomes and Bound to Cross-Linked Envelope

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Antimicrobial peptides: an essential component of the skin defensive barrier.

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Coordinate assembly of lipids and enzyme proteins into epidermal lamellar bodies.

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12 December 2020

Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37.

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12 December 2020

Lamellar body secretory response to barrier disruption

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12 December 2020

Stratum corneum architecture, metabolic activity and interactivity with subjacent cell layers

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12 December 2020

VISUALIZATION OF THE CELL LAYERS OF THE STRATUM CORNEUM

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Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum.

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Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice

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Innate antimicrobial peptide protects the skin from invasive bacterial infection

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Stress alters cutaneous permeability barrier homeostasis

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Production of extracellular enzymes by Microsporum canis and their role in its virulence

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Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies.

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