Skeletal and CNS defects in Presenilin-1-deficient mice (Q28238795)

GOA release 2020-03-11

6

S Tonegawa

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author name string

J Shen

1

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R T Bronson

2

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D F Chen

3

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W Xia

4

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D J Selkoe

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

5

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language of work or name

English

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publication date

16 May 1997

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published in

Cell

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volume

89

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issue

4

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page(s)

629-39

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1 reference

7 January 2021

Developmental regulation of presenilin mRNA expression parallels notch expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Requirement of the paraxis gene for somite formation and musculoskeletal patterning

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Familial Alzheimer's disease associated with S182 codon 286 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Protein topology of presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Regional and cellular presenilin 1 gene expression in human and rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Notch1 is essential for postimplantation development in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Familial Alzheimer's chromosome 14 mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980244-5

7 January 2021