SLC19: the folate/thiamine transporter family (Q28242990)

The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter

Europe PubMed Central

title

SLC19: the folate/thiamine transporter family (English)

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1

Vadivel Ganapathy

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author name string

Sylvia B Smith

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2

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Puttur D Prasad

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3

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language of work or name

English

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publication date

February 2004

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published in

Pfluegers Archiv

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volume

447

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issue

5

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page(s)

641-6

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cites work

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12 December 2020

Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs

1 reference

12 December 2020

Homocysteinemia due to folate deficiency

1 reference

12 December 2020

Molecular cloning of the human placental folate transporter

1 reference

12 December 2020

Mutations in a new gene encoding a thiamine transporter cause thiamine-responsive megaloblastic anaemia syndrome

1 reference

12 December 2020

Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness

1 reference

12 December 2020

Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1).

1 reference

12 December 2020

Structure and organization of the human reduced folate carrier gene

1 reference

12 December 2020

Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake

1 reference

12 December 2020

Restoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function

1 reference

12 December 2020

Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function

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12 December 2020

SLC19A3 encodes a second thiamine transporter ThTr2

1 reference

12 December 2020

Repression of human reduced folate carrier gene expression by wild type p53.

1 reference

12 December 2020

Reduced folate carrier transports thiamine monophosphate: an alternative route for thiamine delivery into mammalian cells

1 reference

12 December 2020

Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization

1 reference

12 December 2020

Structural organization of the human reduced folate carrier gene: evidence for 5' heterogeneity in lymphoblast mRNA.

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12 December 2020

Targeted disruption of Slc19a2, the gene encoding the high-affinity thiamin transporter Thtr-1, causes diabetes mellitus, sensorineural deafness and megaloblastosis in mice

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12 December 2020

Defective high-affinity thiamine transporter leads to cell death in thiamine-responsive megaloblastic anemia syndrome fibroblasts

1 reference

12 December 2020

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

1 reference

12 December 2020

Regulation of the reduced-folate transporter by nitric oxide in cultured human retinal pigment epithelial cells

1 reference

12 December 2020

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium

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12 December 2020

Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5' end heterogeneity

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12 December 2020

Cloning of the human thiamine transporter, a member of the folate transporter family

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12 December 2020

Expression of the reduced folate carrier SLC19A1 in IEC-6 cells results in two distinct transport activities

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12 December 2020

Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells

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12 December 2020

A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells

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12 December 2020

The transmembrane pH gradient drives uphill folate transport in rabbit jejunum. Direct evidence for folate/hydroxyl exchange in brush border membrane vesicles

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12 December 2020

Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates.

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12 December 2020

Topological and functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion

1 reference

12 December 2020

Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells

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12 December 2020

The gene mutated in thiamine-responsive anaemia with diabetes and deafness (TRMA) encodes a functional thiamine transporter

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12 December 2020

Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake

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12 December 2020

Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice

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12 December 2020

Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency.

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12 December 2020

Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier

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12 December 2020

Characterization of a murine high-affinity thiamine transporter, Slc19a2.

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12 December 2020

The spectrum of mutations, including four novel ones, in the thiamine-responsive megaloblastic anemia gene SLC19A2 of eight families

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12 December 2020

Functional role of specific amino acid residues in human thiamine transporter SLC19A2: mutational analysis

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12 December 2020

Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes

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12 December 2020

Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function

1 reference

12 December 2020

Thiamine-responsive megaloblastic anemia syndrome: a disorder of high-affinity thiamine transport.

1 reference

12 December 2020

Localization of a human reduced folate carrier protein in the mitochondrial as well as the cell membrane of leukemia cells.

1 reference

12 December 2020

Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis

1 reference

12 December 2020

Slc19a2: cloning and characterization of the murine thiamin transporter cDNA and genomic sequence, the orthologue of the human TRMA gene

1 reference

12 December 2020

Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis

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12 December 2020

Identification of transcriptional start sites and splicing of mouse thiamine transporter gene THTR-1 (Slc19a2).

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12 December 2020