Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis (Q34144263)

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English	Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis (English)

1 reference

Europe PubMed Central

31 July 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Xiang Y Liu

1

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Europe PubMed Central

31 July 2017

Larry H Matherly

2

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Europe PubMed Central

31 July 2017

language of work or name

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publication date

1 August 2002

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Europe PubMed Central

31 July 2017

Biochimica et Biophysica Acta

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Europe PubMed Central

31 July 2017

1564

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Europe PubMed Central

31 July 2017

2

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Europe PubMed Central

31 July 2017

333-342

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Europe PubMed Central

31 July 2017

Carrier-mediated membrane transport of folates in mammalian cells

1 reference

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Molecular and cellular biology of the human reduced folate carrier

1 reference

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Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake

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Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

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Molecular cloning of the human placental folate transporter

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Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis

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A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.

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Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

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A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

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A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate

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Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

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Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

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Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier

1 reference

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Topological and functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion

1 reference

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Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence

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Localization of cytoplasmic and extracellular domains of Na,K-ATPase by epitope tag insertion.

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Macroscopic models for studies of electrostatic interactions in proteins: limitations and applicability

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Salt bridge interactions: stability of the ionic and neutral complexes in the gas phase, in solution, and in proteins.

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Charge pair interactions in a model transmembrane helix in the ER membrane

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Role of the charge pair aspartic acid-237-lysine-358 in the lactose permease of Escherichia coli

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Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition

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Mutational analysis of the functional role of conserved arginine and lysine residues in transmembrane domains of the murine reduced folate carrier

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10.1016/S0005-2736(02)00467-4

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Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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