Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes (Q28245245)

GOA release 2020-03-11

Tadayuki Tsujita

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John D. Hayes

object named as

John D Hayes

10

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author name string

Vivian Peirce

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Liam Baird

3

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Yuka Matsuyama

4

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Misaki Takaku

5

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Shawn V Walsh

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Julian L Griffin

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Akira Uruno

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Masayuki Yamamoto

Molecular and Cellular Biology

9

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language of work or name

English

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publication date

October 2014

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published in

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volume

34

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issue

20

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page(s)

3800-16

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cites work

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Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes

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The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors

20 March 2017

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Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes

20 March 2017

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The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription

20 March 2017

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Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum

20 March 2017

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Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function

20 March 2017

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Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

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Nrf1 is critical for redox balance and survival of liver cells during development

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Expression of the bZIP transcription factor TCF11 and its potential dimerization partners during development

20 March 2017

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Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

20 March 2017

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Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site

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20 March 2017

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

20 March 2017

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Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

7 April 2017

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Nuclear factor (erythroid-derived 2)-like 2 activation-induced hepatic very-low-density lipoprotein receptor overexpression in response to oxidative stress contributes to alcoholic liver disease in mice

7 April 2017

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Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction.

29 September 2017

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Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression

29 September 2017

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Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.

29 September 2017

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29 September 2017

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29 September 2017

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Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction.

29 September 2017

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Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport

29 September 2017

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The xc- cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance

29 September 2017

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A matter of fat: an introduction to lipidomic profiling methods

29 September 2017

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Depiction of metabolome changes in histidine-starved Escherichia coli by CE-TOFMS.

29 September 2017

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Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

29 September 2017

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Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Acute exposure to 3-methylcholanthrene induces hepatic oxidative stress via activation of the Nrf2/ARE signaling pathway in mice

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

2 June 2018

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Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas.

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187719

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

27 November 2018

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Immunohistochemical localization of cytochrome P450 1A1 in precision-cut rat liver slices after in vitro exposure to beta-naphthoflavone

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Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

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Identifiers

DOI

10.1128/MCB.00110-14

1 reference

2388518

2388518

1 reference

1 reference

1 reference