Interactions of amphetamine analogs with human liver CYP2D6 (Q28246649)

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S V Otton

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T Inaba

3

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W Kalow

4

0 references

E M Sellers

The genetic polymorphism of debrisoquine/sparteine metabolism--clinical aspects

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language of work or name

English

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publication date

1 June 1997

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published in

Biochemical Pharmacology

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volume

53

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issue

11

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page(s)

1605-12

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

7 January 2021

Metabolic polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

"It's the genes, stupid". Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Molecular genetics of the debrisoquin-sparteine polymorphism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Quinidine: potent inhibition of sparteine and debrisoquine oxidation in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Dextromethorphan: enhancing its systemic availability by way of low-dose quinidine-mediated inhibition of cytochrome P4502D6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Inhibition by fluoxetine of cytochrome P450 2D6 activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

The metabolic fate of amphetamine in man and other species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Interindividual and interspecies variation in the metabolism of the hallucinogen 4-methoxyamphetamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Synthesis and neurotoxicological evaluation of putative metabolites of the serotonergic neurotoxin 2-(methylamino)-1-[3,4-(methylenedioxy)phenyl] propane [(methylenedioxy)methamphetamine]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Stereoselective accumulation of hydroxylated metabolites of amphetamine in rat striatum and hypothalamus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Determination of amphetamine, norephedrine, and their phenolic metabolites in rat brain by gas chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Formation of &alpha;-Methyldopamine (&lsquo;Catecholamphetamine&rsquo;) from p-Hydroxyamphetamine by Rat Brain Microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Hydroxyamphetamine. A good drug lost?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphetamine by rat brain microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Sparteine metabolism capacity in human liver: structural variants of human P450IID6 as assessed by immunochemistry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Catalytic activities of human debrisoquine 4-hydroxylase cytochrome P450 (CYP2D6) expressed in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Directional lipophilic character in a series of psychotomimetic phenethylamine derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Spectral and inhibitory interactions of (+/-)-3,4-methylenedioxyamphetamine (MDA) and (+/-)-3,4-methylenedioxymethamphetamine (MDMA) with rat hepatic microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2

Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900014-2