The role of epigenetic inactivation of 14-3-3sigma in human cancer (Q28247253)

Cancer-susceptibility genes. Gatekeepers and caretakers

Europe PubMed Central

title

The role of epigenetic inactivation of 14-3-3sigma in human cancer (English)

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author name string

Dmitri Lodygin

series ordinal

1

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Heiko Hermeking

series ordinal

2

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language of work or name

English

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publication date

April 2005

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published in

Cell Research

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volume

15

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issue

4

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page(s)

237-46

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cites work

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p63 identifies keratinocyte stem cells

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Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes

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Keratinocyte-releasable stratifin functions as a potent collagenase-stimulating factor in fibroblasts.

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Differentiated keratinocyte-releasable stratifin (14-3-3 sigma) stimulates MMP-1 expression in dermal fibroblasts.

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Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

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RNA: guiding gene silencing

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The fundamental role of epigenetic events in cancer

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Immunohistochemical expression of 14-3-3 sigma protein in human urological and gynecological tumors using a multi-tumor microarray analysis

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Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer

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BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells

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Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer

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