Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin (Q28247829)

1

0 references

Ying Liu

2

0 references

Federico Coluccio Leskow

3

0 references

Marcelo G Kazanietz

Journal of Biological Chemistry

5

0 references

language of work or name

English

0 references

publication date

1 July 2005

0 references

published in

0 references

volume

280

0 references

issue

26

0 references

page(s)

24363-70

0 references

cites work

Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Novel "nonkinase" phorbol ester receptors: the C1 domain connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Divergence and complexities in DAG signaling: looking beyond PKC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

beta2-chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Bcr encodes a GTPase-activating protein for p21rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

21 January 2018

Rho proteins and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Role of Rho-family proteins in cell adhesion and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rho and Rac take center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Cell migration: Rho GTPases lead the way

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rho GTPases are over-expressed in human tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

P21-activated kinases in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Regulation of Tiam1-Rac signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rac1 is required for cell proliferation and G2/M progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

Binding of GAP to activated PDGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411629200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411629200

1 reference

Consolidated OpenCitations Corpus – April 2017

4912728

4912728

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference