Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway (Q44489751)

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English	Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 December 2017

Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway (English)

1 reference

Europe PubMed Central

3 December 2017

prostate cancer

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Yuichi Tanaka

1

1 reference

Europe PubMed Central

3 December 2017

M Veronica Gavrielides

2

1 reference

Europe PubMed Central

3 December 2017

Yasuhiro Mitsuuchi

3

1 reference

Europe PubMed Central

3 December 2017

Teruhiko Fujii

4

1 reference

Europe PubMed Central

3 December 2017

Marcelo G Kazanietz

5

1 reference

Europe PubMed Central

3 December 2017

language of work or name

0 references

publication date

24 June 2003

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Europe PubMed Central

3 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

3 December 2017

278

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Europe PubMed Central

3 December 2017

36

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Europe PubMed Central

3 December 2017

33753-33762

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Europe PubMed Central

3 December 2017

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303313200

21 January 2018

Novel "nonkinase" phorbol ester receptors: the C1 domain connection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303313200

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Protein kinase C binding partners

1 reference

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21 January 2018

Adaptor proteins in protein kinase C-mediated signal transduction

1 reference

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Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cells

1 reference

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21 January 2018

Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta

1 reference

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21 January 2018

Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha

1 reference

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21 January 2018

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

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Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway

1 reference

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Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element

1 reference

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Phorbol ester-induced generation of reactive oxygen species is protein kinase cbeta -dependent and required for SAPK activation.

1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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21 January 2018

Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway

1 reference

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21 January 2018

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303313200

21 January 2018

Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

1 reference

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21 January 2018

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

1 reference

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

1 reference

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21 January 2018

PKC-delta inhibits anchorage-dependent and -independent growth, enhances differentiation, and increases apoptosis in CaCo-2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303313200

21 January 2018

Induction of apoptosis by protein kinase C delta is independent of its kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303313200

21 January 2018

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

1 reference

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21 January 2018

Linking protein kinase C to cell-cycle control

1 reference

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21 January 2018

Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage.

1 reference

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21 January 2018

p38 MAP kinase is required for vasopressin-stimulated HSP27 induction in aortic smooth muscle cells

1 reference

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Thrombin activates p38 mitogen-activated protein kinase in vascular smooth muscle cells

1 reference

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Heterogeneity of the signal transduction pathways for VEGF-induced MAPKs activation in human vascular endothelial cells

1 reference

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Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

1 reference

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21 January 2018

Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha

1 reference

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21 January 2018

Lysophosphatidylcholine inhibits insulin-induced Akt activation through protein kinase C-alpha in vascular smooth muscle cells

1 reference

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21 January 2018

A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate

1 reference

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21 January 2018

Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state

1 reference

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Identifiers

10.1074/JBC.M303313200

1 reference

Europe PubMed Central

3 December 2017

1 reference

Europe PubMed Central

3 December 2017

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